Drugs and Receptors

Question 1

Lock and Key

Answer 1

Drug (key) will bind to specific receptor (lock)

Question 2

Receptors are located in..

Answer 2

The plasma membrane

Question 3

Enzyme

Answer 3

Drugs bind to them and either increases or decreases their activity

Question 4

High Potency

Answer 4

Small dose needed to produce response - reduction of side effects

Question 5

BINDS TO ENZYME

Answer 5

Aspirin - It works by blocking the CYCLE-OXYGENASE enzyme. This is responsible for producing prostaglandins, which cause inflammation. Aspirin has anti-inflammatory, analgesic and antipyretic effects.
-insulin receptors

Question 6

BINDS TO RECEPTORS

Answer 6

β-blockers also act on β-receptors. Stops adrenaline from binding to them. They are commonly prescribed for people with high blood pressure or arrhythmias.

Question 7

BINDS TO ION CHANNELS

Answer 7

Anaesthetics block sodium channels. Thus stopping nerve impulse. (LidoCAINE)
-cholinergic nicotinic receptors

Question 8

BINDS TO CARRIER (PUMPS)

Answer 8

Omeprazole - Proton pump inhibitor - stops secretion of stomach acid. Used for gastric ulcers and heartburn.
-adrenoreceptors

Question 9

BINDS TO DNA

Answer 9

Hyprocortisone - Bind to DNA so production of protiens reduced which is what normally cause inflammation.
-steriod receptors

Question 10

BINDS TO FOREIGN PROTEINS

Answer 10

Ketoconazole is an anti-fungal agent which blocks the production of ergosterol which forms part of the fungal cell membrane, resulting in holes appearing and the cell contents leaking out..

Question 11

Agonists

Answer 11

Binds to a receptors causing a response - Mimics chemical in the body.

Question 12

Antagonists

Answer 12

Binds to receptor and stops other chemicals from producing a response.