Drugs of the mind Flashcards
Psychoactive drug
natural or synthetic molecules that alter communication between neurons
Tolerance
Progressive decrease in effectiveness of a drug
- body increases enzymes that remove that drug
- decrease of receptors
- *Body does this to maintain homeostasis
Dependency
Drug is required by user for their physical or psychological well being (drug is now required for homeostasis)
*Nervous system can’t produce normal response b/c of physical changes which causes withdrawal
The drugs that most likely lead to dependency are
cocaine
amphetamine
nicotine
Cocaine
feelings of : Pleasure, confidence, alertness
- Increases dopamine by blocking reuptake
- increases norepinephrine which stimulates fight or flight
Short-lived effect (90 min max) then you feel - anxiety -depression -fatigue
Produces cravings for more cocaine
Health issues of cocaine
CARDIOVASCULAR : Increases hart rate, blood pressure, and interferes with nerves that regulate heartbeat
CAN CAUSE: heart attack or stroke
RESPIRATORY: when u come down off cocaine activity in respiration centers of the brain become depressed
CAN CAUSE: respiratory failure
Amphetamines
Synthetic stimulants that resemble :
Dopamine
Norepinephrine
effects can last hours
controlled doses (prescribe) can increase aletness , concentration, and relive fatigue
Meth
Common street form of amphetamine
Ingested as pills, crushed then snorted, smoked to injected
Meth induces euphoria, feelings of high self esteem, increase libido, insomnia, mania
high-doses : anxiety, paranoia, hallucinations
decreases receptors on the post-synaptic neuron
Effects of meth
Long-term effects to nervous system
Impairment to memory and emotional centers of brain
Hallucinogenic Drug
Visual, auditory, or other hallucinations
ex. ecstasy
effects:
-serotonin (sense of feel-being)
and
-Acetylcholine
(promotes release of norepinephrine -
affects serotonin and dopamine)
Ecstasy physiological
effects
stimulant
- increased heart rate and blood pressure
- cause hyperthermia (increased body temp - heat stroke)
- dehydration (ions become diluted)
**ecstasy pills often contain other drugs
Opiates
Affect opioid receptors
-produces morphine-like effects - pain relief
variety of drugs: Codeine, oxycodone ,hydrocodone ,Vicodin, Percocet, morphine, heroin
easily lead to addiction, dependency = withdrawal
- respiratory distress
Fentanyl
type of opiate
EXTREMELY POTENT
often mixed with heroin
Alcohol
Depresses (slows down) activity of ALL neurons
excitatory neurons run amuck at first
release from inhibitory controls tend to reduce anxiety
Ethanol
Ethanol is the alcohol in every ‘alcoholic’ drink
very small molecule
both lipid and water soluble meaning It readily diffuses into cells
- absorption begins in the stomach (20%)
- food slows absorption (dilutes )