Drugs interfering w/ NT synth Flashcards
p67
1
Q
What drug inhibits dihydroorotate DH?
A
Leflunomide
2
Q
What 2 drugs inhibit IMP DH?
A
Mycophenolate
Ribavirin
3
Q
What drug inhibits ribonucleotide reductase?
A
Hydroxyurea
4
Q
What 2 drugs inhibit de novo purine synthesis?
A
6-MP
Azathioprine (prodrug of 6MP)
5
Q
What drug inhibits thymidylate synthase?
A
5-FU
6
Q
What 3 drugs inhibit dihydrofolate reductase?
A
Methotrexate, trimethoprim, pyrimethamine