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Pharmacology > Drugs Inhibiting Nucleic Acid Synthesis > Flashcards

Drugs Inhibiting Nucleic Acid Synthesis Flashcards

1
Q

Static or cidal?

A

Predominantly cidal

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2
Q

Name the drugs which inhibit nucleic acid synthesis

A

Basic drugs:
Quinolones
Fluoroquinolones

Other drugs:
NiNo And Metro

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3
Q

What are NiNo And Metro

A

NiNo - static drugs
Ni- Nitrofurantoin
No- Novobiocin

And metro- cidal drugs
And- Actinomycin D
Met- Metronidazole
R- Rifampicin
O- clOfazimine

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4
Q

MOA of fluoroquinolones

A

Inhibit type 2 topoisomerases
DNA gyrase (in gram negative bacteria)
Topoisomerase 4 (in gram positive Bacteria)

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Pharmacology (7 decks)

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