Cell Wall Inhibitors

Question 1

Name the basic drugs among drugs targetting cell wall

Answer 1

Beta lactams

Question 2

Name the other drugs in drugs targetting cell wall

Answer 2

FB wall on PC
Fosfomycin
Bacitracin
glycoPeptide antibiotics
Cycloserine

Question 3

Name the beta lactams

Answer 3

Penicillin
Cephalosporin
Monobactam
Carbapenem

Question 4

Name the glycoPeptide antibiotics

Answer 4

Natural glycopeptides:
1. vancomycin
2. Teicoplanin
Semi- synthetic glycoPeptide:
1. Telavancin
2. Dalbavancin
3. Oritavancin

Question 5

MOA of betalactams

Answer 5

Inhibit transpeptidase

Question 6

MOA of fosfomycin

Answer 6

Inhibit enol pyruvate transferase

Question 7

Phosphatase is inhibited by

Answer 7

Bacitracin

Question 8

MOA of glycoPeptides

Answer 8

1. Inhibit transglucosidase

2. Bind to d- ala , d- ala and inhibit peptide bonds

Question 9

Racemase is inhibited by

Answer 9

Cycloserine

Question 10

Red person syndrome is seen in

Answer 10

glycoPeptide antibiotics, due to histamine and cytokine release

Question 11

Vancomycin is the DOC for

Answer 11

1. MRSA
2. Coagulase negative staph aureus
3. Corynebacterium jeikium
4. Enterococcus faecium
5. Clostridium difficile induced PMEC
6. Penicillin allergic patients