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Drugs and the Brain > Drugs in the Synapse and other Things > Flashcards

Drugs in the Synapse and other Things Flashcards

1
Q

What is the function of Monoamineoxidase (MAO) enzymes?

A

Breaks down and metabolizes monoamine neurotransmitters

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2
Q

What is caused by prolonged deprivation of agonist drugs

A

Up regulation

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3
Q

What is the function of a negative allosteric modulator?

A

Modifies and restricts the channel of a receptor

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4
Q

What type of drug prevents metabolism?

A

MAO/Enzyme Inhibitor

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5
Q

What is caused by the chronic use of agonist drugs?

A

Down regulation

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6
Q

What type of drug blocks the site where the neurotransmitter binds to the receptor?

A

Competitive Antagonist

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7
Q

What type of drug modifies and restricts the channel of the receptor?

A

Negative Allosteric Modulator

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8
Q

What is down regulation?

A

A decrease in the total number of receptors?

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9
Q

What is the function of an Antagonist Drug?

A

Blocks neurotransmitters from binding to receptors

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10
Q

What is a VMAT’s function?

A

Carries Neurotransmitters into vesicle

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11
Q

When a drug passes through the blood brain barrier it can_______

A

Work in the brain (be Psychoactive)

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12
Q

Tryptophan is a precursor molecule for what neurotransmitter?

A

5HT/Serotonin

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13
Q

What carries Neurotransmitters into vesicles?

A

VMAT

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14
Q

What is up regulation?

A

An Increase in the total number of receptors?

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15
Q

What type of drug mimics neurotransmitters

A

Agonist Drug

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16
Q

What is the precursor molecule for epinephrine?

17
Q

What type of drug blocks neurotransmitters from binding to receptors?

A

Antagonist Drug

18
Q

What is the precursor molecule for 5HT/Serotonin

A

Tryptophan

19
Q

What is the function of a non-competitive antagonist Drug?

A

Blocks neurotransmitters from inside the channel of the receptor

20
Q

What is the function of a reuptake inhibitor?

A

Blocks the membrane transporter–Prevents the process of Reuptake–prevents neurotransmitters from being absorbed into the presynaptic neuron

21
Q

What is the function of a positive allosteric modulator?

A

Modifies and inflates the channel of a receptor

22
Q

What is the precursor molecule for Dopamine?

23
Q

What is the process of absorbing secreted neurotransmitters back into the presynaptic neuron called?

24
Q

Tyrosine is the precursor molecule for what neurotransmitter?

A

Dopamine, Epinephrine, Norepinephrine

25
Q

What is Reuptake?

A

The process of absorbing secreted neurotransmitters back into the presynaptic neuron

26
Q

What type of drug blocks the membrane transporter/prevents neurotransmitters from being absorbed into the presynaptic neuron?

A

Reuptake inhibitor

27
Q

What type of drug modifies and inflates the channel of a receptor?

A

Positive Allosteric Modulator

28
Q

For a drug to work in the brain (be psychoactive) what must be true?

A

It must pass through the blood brain barrier

29
Q

What breaks down and metabolizes monoamine neurotransmitters?

A

Monoamineoxidase (MAO) enzymes

30
Q

What is the precursor molecule for Norepinephrine?

31
Q

What is the function of an allosteric modulator?

A

Changes the shape of the receptor

32
Q

What is the function of MAO/Enzyme Inhibitor?

A

Prevents Metabolism

33
Q

What is the function of a competitive antagonist Drug?

A

Blocks neurotransmitters from binding to receptors by blocking the site where they bind to the receptor.

34
Q

What is the function of an Agonist Drug?

A

Mimics the neurotransmitter

35
Q

What is a VMAT?

A

Vesicle Monoamine Transporter

36
Q

What is caused by the chronic use of antagonist drugs?

A

Up regulation

37
Q

What type of drug changes the shape of the receptor?

A

Allosteric modulator

38
Q

What is the name of the process for the decrease in the total number of receptors?

A

Down Regulation

39
Q

What type of drug functions by blocking the neurotransmitter from the inside of the channel of the receptor?

A

Non-competitive antagonist

Drugs and the Brain (7 decks)

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