Drugs for the Skin - Acne Flashcards
Topical antibiotics—benzoyl peroxide, clindamycin, and erythromycin—help clear mild to moderate acne by________________.
suppressing growth of Propionibacterium acnes.
Topical retinoids—tretinoin, adapalene, and tazarotene—help clear mild to moderate acne by normalizing hyperproliferation of epithelial cells in hair follicles. These retinoids are not absorbed systemically.
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These are topical retinoids.
Tretinonin
Adapalene
Tazarotene
Topical retinoids help to clear mild to moderate acne by
normalizing hyperproliferation of epithelial cells in hair follicles.
These are not absorbed systemically
Retinoids
Oral antibiotics, including doxycycline and minocycline.
These drugs are reserved for moderate to severe acne.
Benefits of oral antibiotics for acne derive from suppressing growth of P. acnes and from anti-inflammatory actions.
P. acnes and from anti-inflammatory actions.
an oral drug reserved for severe acne, and is highly teratogenic.
Isotretinoin
causes multiple adverse effects, including nosebleeds, inflammation of the lips and eyes, and pain, tenderness, or stiffness in muscles, bones, and joints.
Isotretinoin
HIGHLY teratogenic. Accordingly, all parties involved with the drug—prescribers, patients, pharmacists, and wholesalers—must participate in a risk-management program designed to ensure that isotretinoin is not used during pregnancy.
Isotretinoin