Drugs for the eye - Drugs for Glaucoma

Question 1

A group of diseases characterized by visual field loss secondary to optic nerve damage.

Answer 1

The glaucomas

Question 2

In open-angle glaucoma, optic nerve injury develops _____•

Answer 2

gradually -over years

Question 3

The cause of _____ _____is unknown.

•

Answer 3

nerve damage

Question 4

In angle-closure glaucoma, there is blockage of ______ ___ ___ causing an abrupt rise in_____.

Answer 4

aqueous humor outflow, which causes an abrupt rise in IOP.

Question 5

In the absence of treatment, of angle closure glaucoma, irreversible damage to the _____ _____occurs in __________

Answer 5

optic nerve

1-2 days

Question 6

Major risk factor for angel closure glaucoma

Answer 6

elevated IOP

Question 7

Drug therapy of open angle glaucoma is directed at

Answer 7

Reducing elevated IOP

Question 8

Angle closure glaucoma is treated with drugs to rapidly reduce

Answer 8

IOP

Question 9

Surgically angle closure glaucoma is treated by

Answer 9

Corrective surgery to allow aqueous humor outflow.

Question 10

Drugs reduce IOP by either facilitating but with_____ _____ outflow or by reducing _____ _____ production.

Answer 10

Aqueous humor

Aqueous humor

Question 11

Name the first line agents for topical therapy of open angle glaucoma

Answer 11

Beta blockers
Alpha2 adrenergic agonists
Prostaglandins

Question 12

This topical beta blocker lowers IOP by decreasing aqueous humor reduction

Answer 12

Timolol

Question 13

Can be absorbed in amounts sufficient to cause broncospasm, Bradycardia, and atrioventricular heart block .

Answer 13

Topical beta blockers.

Question 14

Can increase brown pigmentation of the iris and intensify pigmentation of the skin around the eye.

Answer 14

prostaglandins