Drugs for Hyper tension

Question 1

What are the classes of drugs we learned for Hypertension (6)

Answer 1

1) Loop dieretics -> K plus sparing, loop, thiazides
2) Inhibitors of RAAS
3) Calcium channel blockers
4) Adrenergic receptor anatagonsits
5) direct vasodilators
6) central acting agents

Question 2

What are the types of inhibitors of RAAS that we know (4)

Answer 2

1) ACEi
2) Angiotensin Receptor blocekrs
3) REnin inhibitors
4) Aldosterone receptor antagonists

Question 3

What is the ending of ACEi

Answer 3

“pril”
example
Ramipril

Question 4

Adverse side effects of ACEi (5)

Answer 4

1) cough -> bradykinin thing
2) Hypotension
3) Hyperkalemia
4) renal dysfunction
Angioedema

Question 5

Contraindications of ACEi (2)

Answer 5

1) Pregnancy

2) renal artery stenosis

Question 6

ARB Angiotensin receptor blockers End with what

Answer 6

“tan” losartan

Question 7

Angiotensin receptor blockers side effects (4)

Answer 7

1) less cough and less angioedema
2) dizziness and headaches
3) hyperkalemia
4) renal dysfunction

Question 8

Angiotensin receptor blockers Contraindications (1)

Answer 8

1) Pregnant

Question 9

What does renin inhibitors end with

Answer 9

“ren”

Question 10

Side effects renin inhibitors

Answer 10

Diarrhea and angioedema

Question 11

Contraindications for renin inhibitors

Answer 11

pregnancy

Question 12

What are the two types of Calcium channel blockers

Answer 12

1) dihydropyridines

2) non-dihydropyridines

Question 13

What is the MOA of Calcium channel blockers

Answer 13

Decrease HR contraction
dilate SM in vessels
Decrease ca signalling to adrenal decrease release of aldosterone

Question 14

Side effects Ca channel blockers

Answer 14

1) Bradycardia and hypotension-> decreased HR
2) dizziness and headache
3) flushing, peripheral edema, reflex tachycardia-> vasodilation

Question 15

What are contraindication for dihydropyridiens

Answer 15

conditions worsened by tachycardia

severe aortic stenosis

Question 16

Contraindication for non-dihydropyridiens

Answer 16

wolf-parkinisd whie syndrome and av blocks
actue CHF

Sorta can be used for pregnancy

Question 17

What are the 3 adrenergic receptors and their function

Answer 17

1) B1-> increases contraction HR and renin secretion
2) B2-> bronchodilator vasodilation of skeletal muscles arterioles
3) A1-> vasoconstriction and vasoconstriction of non-skeletal muscle vessels

Question 18

(4) types of Beta-blockers

Answer 18

1) Cardioselevtive-> B1 only
2) non-cardio selective_ B2 and B1
3) Mixed alpha and Beta-blockers _> A1 B1 B2
4) partial agonist (b1 agonist)

Question 19

What do beta-blockers end with

Answer 19

Lol

Question 20

Side effects of beta-blockers

Answer 20

1) fatigue
2) bradycardia
3) bronchoconstrction
4) rebond hypertension

Question 21

Contraindication for beta-blockers

Answer 21

Astham\braydcardia

acute CHF

Question 22

Alpha 1 blocker ending

Answer 22

“sin”

Question 23

Central acting agent ending

Answer 23

“dine

Question 24

MOA central acting agent

Answer 24

inhibit presynaptic release of norepinephrine decrease svr hr and sv