Drugs for Endometrial Cancer Flashcards

1
Q

What drugs are used in the treatment of Endometrial Cancer?

A

Medroxyprogesterone

Megestrol

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2
Q

What is the MOA of Megestrol?

A

Megestrol is a synthetic oral progestin that suppresses pituitary LH and increases estrogen degradation. This promotes differentiation and maintenance of the endometrium.

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3
Q

What are the adverse effects associated with Megestrol?

A
Weight gain
PM Sx
Rash 
Tumor flare
Hypercalcemia
Hypercoagulability
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