drugs for ADHD Flashcards

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1
Q

stimulants

A

methyphenidate
dexmethylphenidate
dextroamphetamine
amphetamine mixed salts

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2
Q

methyphenidate short acting

A

ritalin

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3
Q

methyphenidate long acting

A

ritalin LA
concerta
daytrana

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4
Q

amphetamine mixed salts short acting

A

adderal

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5
Q

amphetamine mixed slats long actng

A

adderal XR

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6
Q

nonstimulants

A

atomoxeine

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7
Q

Dx of ADHA

A

6+ symptoms of inattention for >6months to a degree that is maladaptive and inconsistent w/developmental level
or
6+ symptoms of hyperactivity-impulsivity for >6months to a degree that is maladaptive and inconsistent w/developmental level
must present

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8
Q

first line for ADHD

A

methylphenidate

followed by dextroamphetamine and amphetamine mixed salts

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9
Q

which transporter does atomoxetine block?

A

NET

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10
Q

which transporter does methyphenidate block?

A

DAT

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11
Q

which transporters does amphetamines block

A

NET, DAT, SERT

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12
Q

methyphenidate (MPH)

A

active ingredient in majority of stimulate meds
blocks DAT
d-threo enantomer more active

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13
Q

IR-MPH

A

immediate release

can be given as tablets in the am in combo w/long acting formulations or to smooth withdrawal in pm

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14
Q

Ritalin-SR

A

single pulse
up to 8 hours, but variable
usually still prescribed 2x/day

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15
Q

ritalin LA

A

beaded double-pulse biphasic release

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16
Q

Concerta/OROS-MPH

A

osmotic release
12 hrs, less variation
taken once daily

17
Q

daytrana

A

transdermal patch
ADRs: anorexia, insomina, and tics
2hr delay
w/9hr wear lasts for 11.5hrs

18
Q

dextroamphetamine

A

some kids unresponsive to MPH may respond and vice-versa
onset w/in 1hr peak 3 hrs, lasts 5hr
2x/day

19
Q

adderall and adderall XR

A

mixtures of amphetamine salts

adderall XR- biphasic release

20
Q

common ADRs of stimulants

A

delayed sleep onset
HA
decreased appetite/weight loss
infrequent: emotional lability, either new onset or increase in tics

21
Q

atomoxetine

A

aka strattera
neither controlled substance nor stimulant
less effective then stimulants
good for kids who cannot loose weight or parents who do not want controlled substance

22
Q

ADRs atomoxetine

A

somnolence
nausea, vomiting
black box- suicide

23
Q

clonidine and guanfacine

A

clinically useful for Tx of tics and HTN
in kids to manage sleep problems, aggression, and self injury behavior
less effective then stimulants for ADHD, only Tx hyperactivity and impulsivity, not distractibility
must taper off to prevent HTN crisis

24
Q

bupropion

A

CI in seizure disorders

25
Q

TCAs

A

less effective then stimulants for ADHD, only Tx hyperactivity a

26
Q

modafinil

A

non-stimulant w/mild CV effects

hallucinations and SJS can occur