Drugs- By Indication

Question 1

A drug used for local anesthesia (infiltration, nerve block, and spinal). Ester or amide?

Answer 1

Procaine. Ester.

Question 2

A drug used for local anesthesia (spinal and topical). T 1/2 is —- min. Ester or amide?

Answer 2

Tetracaine. 30 min. Ester.

Question 3

A drug used for local anesthesia (infiltration, nerve block). Duration is —— (long or short). Ester or amide?

Answer 3

Chloroprocaine. Short duration. Ester.

Question 4

A drug used for local anesthesia (topical OTC). Ester or amide?

Answer 4

Benzocaine. Ester.

Question 5

A drug used for local anesthesia (all forms of local anesthesia). Ester or amide? Duration 4-6hr.

Answer 5

Bipuvicaine. Amide.

Question 6

A drug used for local anesthesia (all forms of local anesthesia). Ester or amide? More potent than procaine, acts longer than procaine.

Answer 6

Lidocaine. Amide.

Question 7

A drug used for local anesthesia (all forms of local anesthesia). Ester or amide? Similar to bipuvicaine but fewer cardio side fx.

Answer 7

Ropivicaine. Amide.

Question 8

A drug used to treat idiopathic intracranial HTN, also a loop diuretic.

Answer 8

Furosemide

Question 9

A drug used to treat idiopathic intracranial HTN, also a CAi.

Answer 9

Acetazolamide

Question 10

TWO drugs that can used for acute muscle spasm due to tissue injury

Answer 10

Cyclobenzaprine

Diazepam (usefulness ltd by sedative effects)

Question 11

A drug used to treat cerebral palsy.

Answer 11

Diazepam (benzodiazepine)

Question 12

Four drugs that can be used to treat spinal cord injury

Answer 12

Benzodiazepine
Baclofen
Tizanidine
Dantrolene

Question 13

Four drugs that can be used to treat MS

Answer 13

Baclofen
Tizanidine
Dantrolene
Dalfampridine

Question 14

Dopamine precursor used to treat PD and dystonia

Answer 14

Levodopa

Question 15

Inhibitor of L-dopa conversion to dopamine, used in combination with other drugs to treat PD and dystonia.

Answer 15

Carbidopa

Question 16

Inhibitor of COMT used in combo with other drugs to treat PD

Answer 16

Entacapone

Question 17

Four dopamine agonists (one bolded) used to treat PD

Answer 17

Ropinirole (bolded)
Pramipexole
Rotigotine
Apomorphine

Question 18

mACHr antagonist used to treat PD, especially tremor of PD (one bolded, one unbolded)

Answer 18

Trihexyphenidyl (bolded)

Benztropine

Question 19

MAO-B inhibitors (one bolded, one unbolded) used to treat PD.

Answer 19

Selegiline (bolded)

Rasagiline

Question 20

Two drugs used to treat drug-induced EPS.

Answer 20

Selegiline and Rasagiline (both are MAO-B inhibitors)

Question 21

A NMDAr antagonist used to treat PD and fatigue symptoms.

Answer 21

Amantadine

Question 22

One drug used to treat chorea and tics that is a VMAT2 antagonist.

Answer 22

Tetrabenazine

Question 23

Two drugs that are used to treat chorea and tics (one bolded, one unbolded) that are classified as “antipsychotics”.

Answer 23

Haloperidol (bolded)

Olanzapine

Question 24

Two drugs used to treat tics that are alpha2 agonists

Answer 24

Clonidine (bolded)

Guanfacine

Question 25

A muscle relaxant used to treat tics.

Answer 25

Botulinum toxin

Question 26

Six drugs used to treat tics, and their classifications.

Answer 26

Botulinum toxin (muscle relaxant) Guanfacine and Clonidine (alpha2 agonists) Tetrabenazine (VMAT2 antagonist) Haloperidol and Risperidone (antipsychotic/block D2)

Question 27

Three drugs used to treat chorea, and their classifications.

Answer 27

Tetrabenazine (VMAT2 antagonist) | Haloperidol and Risperidone (antipsychotic/block D2)

Question 28

Used to block essential tremor, beta antagonist.

Answer 28

Propranolol

Question 29

Used to treat essential tremor, indirectly stimulates GABAa

Answer 29

Primidone (metabolite stimulates GABAa)

Question 30

Used to treat essential tremor, prolongs inactivated state of NaV channels

Answer 30

Topiramate

Question 31

Used to treat essential tremor, binds to CaV channels

Answer 31

Gabapentin

Question 32

Three drugs used to treat essential tremor that are BDZs

Answer 32

Benzodiazepine Alprazolam Clonazepam

Question 33

Seven drugs used to treat Essential tremor and their classification.

Answer 33

Propranolol (beta blocker) Primidone (indirect GABAa agonist- anti-epileptic)) Topiramate (NaV inactivator?- anti-epileptic) Gabapentin (CaV binder- anti-epileptic) BDZ, Alprazolam, Clonasepam (GABAa allosteric binders? Benzodiazepines. increase GABA-mediated IPSPs)

Question 34

Drug used in later stage PD, in combination with a second drug

Answer 34

Levodopa, carbidopa

Question 35

Used as monotherapy in early PD (2 drugs)

Answer 35

Ropinirole and other DA agonists, Amantadine

Question 36

Used in patients with prominent behavioral problems

Answer 36

Clonidine and Guanfacine