Drugs And Translocations Flashcards by Sabrina Wiser

Q

(8;14)

A

Burkitt’s lympoma

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Q

(8;21)

A

AML

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Q

(9;22)

A

CML

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Q

(11;14)

A

Mantle Cell Lymphoma

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Q

(12;21)

A

ALL

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Q

(14;18)

A

Follicular Lympoma

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Q

(15;17)

A

APL

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Q

Rituximab

A

CLL/SLL (works against CD20)

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Q

To avoid tumor lysis syndrome (2)

A

Aggressive IV fluids

2. Allopurinol

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Q

How to treat tumor lysis syndrome

A

Treat each electrolyte abnormalities (high K/P/urea + low Ca)

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Q

ATRA

A

APL

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Q

How to treat congestive splenomegaly secondary to Cirrhosis

A

Reduce portal vein congestion via shunt

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Q

DDAVP / desmopressin

A

Von Willebrand Disease

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Q

How to treat major bleeding in vWF disease

A

VWF: recombinant or plasma-derived

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Q

Emicizumab

A

Hemophilia A

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Q

Heparin inhibits which four factors?

A

2, 9, 10, 11

Q

Xarelto, rivaroxaban, apixaban, endoxaban

A

Factor Xa inhibitors

Q

Dabigatran

A

Direct thrombin inhibitor

Q

Warfarin: blocks what four factors

A

(Vitamin K dependent factors) 2, 7, 9, 10

Q

Hydroxyurea

A

Sickle cell anemia

Q

Epoetin alfa

A

Anemia due to: CKD, cancer, HIV treatment

Q

Eculizumab

A

PNH and HUS

Q

Filgrastim, sargramostim, plerixafor

A

Severe neutropenia

Q

Oprelvekin, romiplostim, eltrombopag

A

Thrombocytopenia

Drug for CLL/SLL

Rituximab

Drug for APL

ATRA

Drug for Von Willebrand Disease

DDAVP/desmopressin

Drug for hemophilia A

Emicizumab

Drug for anemia due to: CKD, CA, or HIV treatment

Epoetin Alfa

Drug for PNH and HUS

Eculizumab

Three drugs for severe neutropenia

1. Filgrastim 2. Sargramostim 3. Plerixafor

Three drugs for thrombocytopenia

1. Oprelvekin 2. Romiplostim 3. Eltrombopag

Drug for CML

Imatinib (Gleevec)