Drugs

Question 1

Digoxin use?

Answer 1

Heart Failure

Arrhythmia

Question 2

Digoxin method of action

Answer 2

Cardiac Glycoside and inhibits Na/K ATPase pump increasing force of cardiac contraction

Question 3

Losartan use?

Answer 3

Hypertension and when ACEinhibitors are unsuitable

Question 4

Losartan method of action

Answer 4

Blocks angiotensin II receptors causing vasodilation, which reducing vasopressin, which decreases aldosterone deducing BP

Question 5

Furosemide use?

Answer 5

Edema
Congestive heart failure
Resistant hypertension

Question 6

Furosemide method of action?

Answer 6

Loop diuretic and inhibits electrolyte re-absorption in ascending limb in loop of henle and in distal tubules. increases sodium and hydrogen excretion.

Question 7

Simvastatin use

Answer 7

Hyperlipidaemia

Hypercholesterolaemia

Question 8

Simvastatin method of action

Answer 8

Competitive inhibitor of HMG-COa reductase, which reduces cholesterol synthesis

Question 9

Spironolactone use

Answer 9

Edema
Ascites
Congestive heart failure
Nephrotic syndrome

Question 10

Spironolactone method of action

Answer 10

Competes for aldosterone receptors in the cortical collecting duct which decreases reabsorption of sodium and water, while decreasing potassium secretion

Question 11

Amiodarone use

Answer 11

Arrhythmias
Paroxysal supraventricul, nodal and ventricular tachycardia
Atrial fibrillation and flutter