Drugs Flashcards
Types of Drug
2
Agonists -
(Nicotine, Cannabis, Heroin), Imitate neurotransmitters to activate the reward pathway, Much more powerful than natural neurotransmitters
Antagonists - (Amphetamines) Massively boost the number of normal neurotransmitters
Nicotine
2
Mimics Acetycholine
Binds to the Acetycholine receptor, which excites the neuron, releasing dopamine which then excites the other neurons in the reward pathway
Amphetamines
Blocks the reuptake of dopamine so it builds up in the synaptic cleft
Neurobiology of drugs SODA
S - Olds & Milner (1954), Rats had electric wires connected to the septum (pleasure centre of the brain). They could trigger a pleasurable shock by pressing a lever, which they did over and over instead of other sources of pleasure e.g. food
O - Reductionist. Humans do drugs for reasons (coping etc.), not just the experience of pleasure that animals have. Neurobiological explanations ignore this and treat us as slaves to our own neurobiology
D - Freud thinks that we take drugs for sexual pleasure (eros) that we cannot achieve e.g. defence mechanism
A - has led to biological treatments for addiction. DRT gives users a similar drug in a controlled way, with the dosage eventually being cut over time.