Drugs

Question 1

What are the non-depolarising blockers?

Answer 1

• Atracurium
• Mivacurium
• Pancuronium
• Vecuronium
• Rocuronium

Question 2

Non depolarising blocker(s) with medium onset and medium duration

Answer 2

• Vecuronium

* Atracurium

Question 3

Non depolarising blocker(s) fast onset and short duration

Answer 3

• Mivacurium

Question 4

Non depolarising blocker(s) with medium onset and a long duration

Answer 4

• Pancuronium

Question 5

Non depolarising blocker(s) with a fast onset and medium duration

Answer 5

• Rocuronium

Question 6

Pancuronium

Answer 6

• Medium onset
• Long duration
• Tachycardia
• Hepatic metabolism
• Non depolarising blocker - antagonist

Question 7

Vecuronium

Answer 7

• Medium onset
• Medium duration
• Few side effects
• Hepatic metabolism
• Non depolarising blocker - antagonist

Question 8

Rocuronium

Answer 8

• Fast onset
• Medium duration
• Tachycardia
• Unchanged in bile/urine
• Non-Depolarising blocker - antagonist

Question 9

Atracurium

Answer 9

• Medium onset
• Medium duration
• Hypertension / bronchospasm
• Ester hydrolysis/ Hoffman elimination
• Non-depolarising blocker - antagonist

Question 10

Mivacurium

Answer 10

• Fast onset
• Short duration
• Hypertension / Bronchospasm
• Plasma cholinesterase
• Non depolarising blocker - antagonist

Question 11

Suxamethonium

Answer 11

• Fast onset
• Short acting
• Bradycardia
• malignant Hypothermia
• Post operative Myalgia
• Increases intraocular pressure
• Cardiac dysrhythmia
• Depolarising blocker -agonist

Question 12

Medium acting anticholinesterase drug(s)

Answer 12

• Neostigmine
• Pyridostigmine
(Quaternary amines)

Question 13

Long acting anticholinesterase drug(s)

Answer 13

• Dyflos
• Parathon
(organophosphates)

Question 14

Neostigmine

Answer 14

• Medium acting
• Anticholinesterase
• Quaternary amine
• SLUDGE, bradycardia, hypotension, pupil constriction, bronchoconstriction

Question 15

Pyridostigmine

Answer 15

• Medium acting
• Anticholinesterase
• Quaternary amine
• SLUDGE, Bradycardia, Bronchoconstrion, Pupil constriction (miosis), Hypotension

Question 16

Dyflos

Answer 16

• Long acting anticholinesterase
• organophosphate
• SLUDGE, Bradycardia, Hypotension, miosis, Bronchoconstriction
• Potentially irreversible

Question 17

Parathion

Answer 17

• Long acting anticholesterase
• Organophosphate
• SLUDGE, Bradycardia, Hypotension, Miosis, Bronchoconstriction
• Potentially irreversible

Question 18

Non-selective muscarinic agonists

Answer 18

• Pilocarpine

* Bethanechol

Question 19

Non-selective muscarine antagonists

Answer 19

• Atropine
• Glycopyrronium
• Hyoscine Hydobromide
• Hyoscine Butylbromide
• Ipratropium
• Tropicamide

Question 20

Which non selective muscarinic antagonists affect the CNS?

Answer 20

• Atropine

* Hyoscine hydrobromide

Question 21

Which non-selective muscarinic antagonists cannot cross the blood brain barrier?

Answer 21

• Glycopyrronium
• Hyoscine butyl bromide
• Ipratropium

Question 22

Pilocarpine

Answer 22

• Non-selective muscarinic agonist
• Constricts pupils
• Decreases intraocular pressure (Treats Glaucoma)
• Increases salivation (Xerostomia)

Question 23

Bethanechol

Answer 23

• Non-selective muscarinic agonist
• Increases smooth muscle tone
• Treats bladder hypotonia

Question 24

Atropine

Answer 24

• Non-Selective muscarinic antagonist
• Treats bradycardia
• Treats anticholinesterase poisoning
• Adjunct for anaesthesia

Question 25

Nifedipine

Answer 25

• Dihydropyridine
• Voltage gated Ca 2+ channel blocking drugs
• Treats: Hypertension, Migraine, Atherosclerosis

Question 26

Dantrolene

Answer 26

• Ryanodine
• Spasmolytic drug acting as a skeletal muscle relaxant
• Used to treat (sarcoplasmic reticulum)
• Muscle spasm
• Malignant hypothermia