Drugs Flashcards
What are some of the side effects associated with nitrates such as GTN?
Dizziness
Flushing
Hypotension
Headache
What are some of the side effects associated with ACE inhibitors?
Profound hypotension Non productive cough Altered taste Gastro intestinal upset Renal impairement Hyperkalaemia
What are some of the side effects of beta blockers?
Bradycardia Night mares Impotence Peripheral vasoconstriction Bronchoconstriction
What are some of the side effects of statins?
Deranged liver function tests
Gastro intestinal disturbances
Myalgia
Myositis
What is a side effects from anti platelets?
Gastric irritation
Name 2 statins.
Atorovastatin
Simvastatin
Name 3 beta blockers
Bisoprolol
Atenolol
Metoprolol
Name 2 anti platelets.
Apsirin
Clopidogrel
Name 2 ACE inhibitors
Ramipril
Perindopril
what are some of the adverse drug reactions with beta blockers?
hypotension with other anti-hypertensive medications
bradycardia with other rate limiting medications
mimic and mask hypoglycaemic actions of insulin
NSAIDS antagonise antihypertensive actions
what effect does NSAIDS have on beta blockers and other anti hypertensives?
antagonise their effect
what are the contraindications for the use of calcium channel blockers?
never use for immediate release
may increase mortality if given post MI in people with impaired LV function
what are some of the side effects of CCB?
ankle oedema (doesn’t respond to diuretics)
headache
flushing
palpitations
how do nitrates cause vasodilation?
they release NO which simulates the release of cGMP which produces smooth muscle relaxation
what affects does GTN have which relieves angina?
arteriolar dilation
peripheral venodilation
relieving coronary vasospasm
redistributing myocardial blood flow to ischaemic areas of the myocardium
