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GASTROENTEROLOGY SCE > Drugs > Flashcards

Drugs Flashcards

1
Q

How does cocaine cause peptic ulcer disease

A

Secondary to mucosal ischaemia

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2
Q

Which ant-acid is not metabolised in the liver (no first pass metabolism)

A

Nitazidine

Can be given at bedtime

100% bioavailability

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3
Q

Which ant-acid has the highest avidity for the P450 system and thus more drug interactions

A

Omeprazole (CPY219)

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4
Q

Which ant-acid medication require dose reduction when the creatinine clearance falls below 50?

A

HR2 antagonists

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5
Q

Which drug can reduce serum zinc levels

A

Penicillamine - increases renal clearance of zinc

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6
Q

How does obeticholic acid work

A

FXR receptor agonist

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7
Q

What drug should be stopped if the pt develops focal nodular hyperplasia of liver?

A

Azathioprine

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GASTROENTEROLOGY SCE (11 decks)

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