Drugs Flashcards

1
Q

What can diuretics be used for?

A

HF snd hypertension

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2
Q

What can beta blockers be used for?

A

Angina, hypertension and CCF

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3
Q

What can ACE inhibitors be used for?

A

CCF and hypertension

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4
Q

What can Calcium antagonists be used for?

A

Hypertension and angina

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5
Q

What are nitrates used for?

A

CCF and angina

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6
Q

when can diuretics not be used?

A

If the patient has gout

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7
Q

When are beta blockers contraindicated?

A

Asthma

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8
Q

Which drugs are anti-hypertensives?

A

Thiazide diuretics
Alpha/Beta blockers
ARBs/ACE inhibitors
calcium antagonists

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9
Q

Which drugs are anti-thrombotics?

A

Antiplatlets
Fibrinolytics
Anti-coagulants

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10
Q

Give examples of antiplatlets

A

Aspirin, clopidogril

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11
Q

Give examples of Fibrinolytics

A

tPA or streptokinas

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12
Q

Give examples of anti-coagulants

A

Riveroxiban or warfarin

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13
Q

Which drugs are anti-cholesterols?

A

Statins and fibrates

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14
Q

Which drugs are anti-anginas

A
Nitrates
Beta blockers
Calcium antagonists 
Nicorandil
Ranolazine
Ivabradine
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15
Q

What do diuretics do?

A

Block Na+ reabsorption

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16
Q

Give an example of a thiazide diuretic

A

bendrofluazide

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17
Q

what are thiazide diuretics used for?

A

Hypertension

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18
Q

Give an example of a loop diuretic

A

Furosemide

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19
Q

What is furosemide used for?

A

Heart failure

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20
Q

What are the side effects of diuretics?

A

Tired, hypokalaemia, arrhythmias, diabetes and gout due to increased uritic acid

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21
Q

How do beta blockers work?

A

Blocks B1 and B2 adrenoreceptors

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22
Q

Give an example of a B1 receptor selective beta blocker

A

Atenolol

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23
Q

What is Atenolol used for?

A

Angina, hypertension and herat failure

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24
Q

Give an example of a non-selective beta blocker

A

Propranol

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25
What is propanol used for?
Thyroxitosis
26
What are the side effects of beta blockers?
Tired and may worsen HF in the short term
27
Give an example of a calcium antagonist
Dihydrophines e.g. amlodipine | Veramparil
28
what is amlodipine used for?
hypertension and angina
29
What are the side effects of amlodipine?
Ankle oedema
30
When should verapamil be avoided?
When also using beta blockers
31
Give an example of an alpha blocker
Doxazosin
32
What are the side effects of Doxazosin
Postural hypertension
33
How do ACE inhibitors work?
Prevents the conversion of angiotension I to angiotensin II
34
Given an example of an ACE inhibitor
Lisinopril
35
What are the side effects of ACE inhibitors?
Cough, renal dysfunction and angioneurmtic oedema
36
When should ACE inhibitors and ARBs never be used?
In pregnancy
37
How do ARBs work?
Block angiotensin II receptors
38
Give an example of an ARB
Losartan
39
What are ARBs used for?
Hypertension and heart failure
40
What are the side effects of ARBs?
Renal dysfunction
41
Give examples of nitrates
Isosobride and mononitrate
42
What are the side effects of nitrates?
Headaches and hypotension
43
How often should be left nitrate free in a day and why?
8 hrs a day to avoid tolerance forming
44
Give examples of antiplatlet agents
aspirin and clopidogril
45
What are antiplatlets used for?
Angina, acute MI, TIA and for those who are high risk of CVA
46
What are the side effects of Anti-platlets?
Haemorrhage and peptic ulcers
47
How do anticoagulants work?
Prevent formation of a new thrombosis
48
How should heparin be given?
IV only
49
What does warfarin do?
Blocks clotting factor 2,7,9 and 10 - used in DVT, pulmonary embolisms and NSTEMIs
50
How does riveroxiban work?
Factor Xa inhibitor - Xa converts prothrombin II into thrombin
51
How does dabigatran work?
Thrombin factor IIa inhibitor
52
How do fibrynolytics work?
Dissolve formed clots
53
Give examples of fibrinolytics
Streptokinase or tissue plasminogin activators
54
How do statins work?
Blocks HMG Co reductase
55
What are statins used for?
Hypercholesterolaemia, diabetes, angina, MI and TIA
56
What are the side effects of statins?
Myopathy or can cause renal failure
57
Give an example of a fibrate
Bezafibrate
58
What should be used for SVTs?
Adenosine
59
What should be used for ventricular/supraventricular arrhythmias?
Beta blockers, flecainide or amiodarone
60
What are the side effects of amiodarone?
Phototoxicity, pulmonary fibrosis and thyroid abnormalities
61
How does digoxin work?
Blocks AV conduction - used in AF
62
Why is digoxin bad in excess?
Reduces HR and so can cause bradycardia and heart block
63
What is a side effect of digoxin?
Increases ventricular irritability which produces ventricular arrhythmias
64
How does digoxin toxicity clinically present?
Nausea and vomiting, yellow vision, bradycardia and ventricular arrhythmias