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Host Defense Test 1-2 > Drugs > Flashcards

Drugs Flashcards

1
Q

Penicillin

A

“Pencil Man” with “PBJ (PBP) cape” is driving at the “trans-pepsi-can linking the cell wall with chains” . He has a “hiker sensitive” man in his trunk looking at the “beta-black Ace(lactamase) senstitive” fish.

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2
Q

Cephalosporins

A

“chef spore” head is “breaking the wall” with the “beta-black” fish. He is baking “bacteria sliders (bactericidal)” and there’s an “amigo glider stabbing a kidney” (aminoglycoside)

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3
Q

Cephalosporins 1 generation

A

Cephalasporin 1 is a “chef-zorro (cefazolin)” and “chef-flexing (cephalexin)” Who is looking after the “graham cracker angel”

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4
Q

Cephalosporins 3rd generation

A

“Chef-spore” in a “3 tree” with his “chef-taxes (cefotaxime)” and “chef-tri-ax” and the “Chef-taz-dime” are all trying to get the “graham devil with resistance to Beta-black fish”

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5
Q

Cephalosporin 5th generation

A

“Chef-spore 5 hand” is cutting up the “beta-black fish” and feeding it to the “resistant bacteria”

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6
Q

Which cephalosporin generation crosses the BBB?

A

3rd

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7
Q

What will make Cephalosporin toxic?

A

Alcohol

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8
Q

What is good about Carbapenems? (car penny)

A

B-lactamase resistant (the car-penny is running over the Beta-black Ace fish)

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9
Q

How do Vanco, Dapto, Bacitracin work?

A

Cell wall inhibitor

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10
Q

AZtreonam

A

“AZ tree” with “PBJ (pbp)” sandwiches is “disrupting the wall” and the “Mono-man backgammon (monobactam)” is fishing with the “resistant beta-black Ace” fish

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11
Q

Protein Synthesis Inhibitors

A

“Protein Bar’s in Jail” and the party starts….with “Dirty 30’s” hanging on to the “amigo-glider” who is riding the “tetris-cycle” The “50’s rapper” is having his own party. “Linen-soldier (linezolid)” is giving the towels, and the “lincoln-mice” and the “cleaning mice” and the “earth throwing mice” and the “chlorine-fanny pack (chloraphenicol)”

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12
Q

What does Vancomycin inhibit?

A

Cell wall mucopeptide (Van-mice taking down the “wall of mucous Pepsi”

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13
Q

What is NOT Vanco?

A

Nephro toxic
Oto toxic
Thrombophlebitis

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14
Q

Fluoroquinolones

A

the “flower queen” is chasing the “top DNA gyrase” but she can’t catch it because she ruptures her “tendon”

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15
Q

What is the toxicity of Nitrofurantoin?

A

Nephrotoxic

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16
Q

Metronidazole

A

The “Metro-knight” is chasing the “trichomonas trike” and the train ruins the “DNA” track it’s on.

17
Q

What’s the mechanism for sulfonamides? Toxicities?

A

The “G6-Police Department (G6PD)” is running to the “sensitive hiker” who is lighting the “DNA synthesis” track on fire with a “sulfur” match
Stops DNA synthesis
Hypersensitivity (G6PD)

18
Q

What does Trimethoprim do?

A

“Meth addict on a trike” runs over the “DNA track” breaking it up.
Stops DNA synthesis

19
Q

What does Daptomycin do? toxicity?

A

The “dapper mice” are eating the “cell wall” and becoming “rabid mice”
Disrupts cell membrane
Rhabdomyolysis

20
Q

What does Polymixen do?

A

“mixes” the osmotic gradient disrupting cell wall

Renal tubular necrosis

21
Q

Amphotericin B

A

“Amphibian Terrorist Bee” shoots “holes in everything” and the amphibian gets “fever and chills”

22
Q

Nystatin

A

“Nice Satan” shoots holes with the frogs guns (pore forming)

23
Q

Azoles

A

“Inhibiting chains on Eggo-stairs (inhibiting egosterol)” by the “A-hole”

24
Q

Terbinafine

A

“Turbine-in Fins” with the “inhibiting Square Whale Epoxidase” and he “inhibits Eggo-stairs”

25
Q

Flucytosine

A

the “Flute-side-toe” is dragging the “inhibited DNA” and the “inhibited Bone arrows”

26
Q

Caspofungin

A

The ghost casper “Funion” is inhibiting the “beta glue can” fish from “creating a “cell wall”

27
Q

Griseofulvin

A

“Grizzly full” bear is chasing after the “Pea-450 inducer’’ rocket.

28
Q

What does Amantadine do?

A

A-man to dine doesn’t take off his coat (blocks uncoating)

29
Q

Foscarnet

A

The “fox car with net” is inhibiting the “DNA Polly Parrot” and the “Side-toe-mega virus”

30
Q

Docasanole

A

“dog in a Hole” stops the virus from “getting in his hole”

31
Q

Interferon Alpha

A

Inhibits Viral replication

Flu symptoms

32
Q

Ribavirin

A

“Robber-virus” gets away and “blocks the DNA”

33
Q

What drugs are used for Hep B?

A

Reverse Transcriptase

34
Q

What does Boceprevir/Simeprevir do?

A

Protease Inhibitor

Host Defense Test 1-2 (3 decks)

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