Drugs Flashcards
Penicillin
“Pencil Man” with “PBJ (PBP) cape” is driving at the “trans-pepsi-can linking the cell wall with chains” . He has a “hiker sensitive” man in his trunk looking at the “beta-black Ace(lactamase) senstitive” fish.
Cephalosporins
“chef spore” head is “breaking the wall” with the “beta-black” fish. He is baking “bacteria sliders (bactericidal)” and there’s an “amigo glider stabbing a kidney” (aminoglycoside)
Cephalosporins 1 generation
Cephalasporin 1 is a “chef-zorro (cefazolin)” and “chef-flexing (cephalexin)” Who is looking after the “graham cracker angel”
Cephalosporins 3rd generation
“Chef-spore” in a “3 tree” with his “chef-taxes (cefotaxime)” and “chef-tri-ax” and the “Chef-taz-dime” are all trying to get the “graham devil with resistance to Beta-black fish”
Cephalosporin 5th generation
“Chef-spore 5 hand” is cutting up the “beta-black fish” and feeding it to the “resistant bacteria”
Which cephalosporin generation crosses the BBB?
3rd
What will make Cephalosporin toxic?
Alcohol
What is good about Carbapenems? (car penny)
B-lactamase resistant (the car-penny is running over the Beta-black Ace fish)
How do Vanco, Dapto, Bacitracin work?
Cell wall inhibitor
AZtreonam
“AZ tree” with “PBJ (pbp)” sandwiches is “disrupting the wall” and the “Mono-man backgammon (monobactam)” is fishing with the “resistant beta-black Ace” fish
Protein Synthesis Inhibitors
“Protein Bar’s in Jail” and the party starts….with “Dirty 30’s” hanging on to the “amigo-glider” who is riding the “tetris-cycle” The “50’s rapper” is having his own party. “Linen-soldier (linezolid)” is giving the towels, and the “lincoln-mice” and the “cleaning mice” and the “earth throwing mice” and the “chlorine-fanny pack (chloraphenicol)”
What does Vancomycin inhibit?
Cell wall mucopeptide (Van-mice taking down the “wall of mucous Pepsi”
What is NOT Vanco?
Nephro toxic
Oto toxic
Thrombophlebitis
Fluoroquinolones
the “flower queen” is chasing the “top DNA gyrase” but she can’t catch it because she ruptures her “tendon”
What is the toxicity of Nitrofurantoin?
Nephrotoxic
Metronidazole
The “Metro-knight” is chasing the “trichomonas trike” and the train ruins the “DNA” track it’s on.
What’s the mechanism for sulfonamides? Toxicities?
The “G6-Police Department (G6PD)” is running to the “sensitive hiker” who is lighting the “DNA synthesis” track on fire with a “sulfur” match
Stops DNA synthesis
Hypersensitivity (G6PD)
What does Trimethoprim do?
“Meth addict on a trike” runs over the “DNA track” breaking it up.
Stops DNA synthesis
What does Daptomycin do? toxicity?
The “dapper mice” are eating the “cell wall” and becoming “rabid mice”
Disrupts cell membrane
Rhabdomyolysis
What does Polymixen do?
“mixes” the osmotic gradient disrupting cell wall
Renal tubular necrosis
Amphotericin B
“Amphibian Terrorist Bee” shoots “holes in everything” and the amphibian gets “fever and chills”
Nystatin
“Nice Satan” shoots holes with the frogs guns (pore forming)
Azoles
“Inhibiting chains on Eggo-stairs (inhibiting egosterol)” by the “A-hole”
Terbinafine
“Turbine-in Fins” with the “inhibiting Square Whale Epoxidase” and he “inhibits Eggo-stairs”
