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Metabolism and Nutrition > Drugs > Flashcards

Drugs Flashcards

1
Q

ezetimibe

A

intestinal cholesterol absorption inhibitor. upregulates LDL-R

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2
Q

fibrates

A

activate LPL and lower TG

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3
Q

beta-sitosterol

A

compete with cholesterol in micelle formation. poorly absorbed.

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4
Q

campesterol

A

compete with cholesterol in micelle formation. poorly absorbed.

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5
Q

stigmasterol

A

compete with cholesterol in micelle formation. poorly absorbed.

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6
Q

sitostanol

A

compete with cholesterol in micelle formation. poorly absorbed.

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7
Q

compestanol

A

compete with cholesterol in micelle formation. poorly absorbed.

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8
Q

stigmastanol

A

compete with cholesterol in micelle formation. poorly absorbed.

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9
Q

cimetidine

A

h2-receptor blocker to inhibit acid secretion

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10
Q

misoprostol

A

prostaglandin E1 analogue; used for protection in peptic ulcers

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11
Q

sucralfate

A

forms an ulcer-adherent complex with proteins; ulcer protection and treatment

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12
Q

pectin

A

anti-diarrhea (adsorbent)

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13
Q

guar gum

A

anti-diarrhea (adsorbent)

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14
Q

bismuth (think pepto bismol)

A

anti-diarrhea (adsorbent)

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15
Q

codeine

A

pain killer, anti-diarrheal (antimotility)

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16
Q

loperamide

A

anti-diarrhea (anti cholinergic, antimotility)

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17
Q

diphenoxylate

A

anti-diarrhea (anti cholinergic, antimotility)

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18
Q

aluminum

A

antacid; becomes insoluble with phosphate and causes constipation

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19
Q

magnesium

A

antacid; causes diarrhea

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20
Q

maalox

A

antacid; middle ground of side effects

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21
Q

calcium

A

may cause renal stones and constipation

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22
Q

-tidine

A

acid reflux relief; H2 receptor blockers

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23
Q

-prazole

A

proton pump inhibitors; bind irreversibly

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24
Q

verapamil

A

calcium channel blocker; antispasmodic in GI, side effects in CV

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25
Q

diltiazem

A

calcium channel blocker; antispasmodic in GI, side effects in CV

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26
Q

pinaverium bromide

A

calcium channel blocker; selective for GI

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27
Q

nitroglycerin

A

relax SMCs by converting to NO

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28
Q

buscopan

A

block muscarinic receptor on SMCs to block effects of Ach

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29
Q

TCA (tricyclic antidepressant)

A

GI pain

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30
Q

SSRI (selective serotonin reuptake inhibitor)

31
Q

amitriptyline

A

TCA; GI pain med

32
Q

nortriptyline

A

TCA; GI pain med

33
Q

desipramine

A

TCA; GI pain med

34
Q

imipramine

A

TCA; GI pain med

35
Q

citalopram

A

SSRI: GI pain med

36
Q

fluoxetine

A

SSRI: GI pain med

37
Q

paroxetine

A

SSRI: GI pain med

38
Q

sertraline

A

SSRI: GI pain med

39
Q

metoclopramide

A

prokinetic (proximal gut) and anti-emetic; weak 5HT4 agonist and 5HT3 antagonist

40
Q

domperidone

A

prokinetic (proximal gut) and anti-emetic

41
Q

erythromycin

A

prokinetic; acts on motilin receptors on SMCs and Ach neurons

42
Q

prucalopride

A

prokinetic in distal bowel

43
Q

psyllium (seed husks)

A

constipation relief

44
Q

bran

A

constipation relief

45
Q

docusate sodium

A

stool softener

46
Q

bisacodyl

47
Q

sennoside

48
Q

gravol (dimenhydrinate)

A

antiemetic; anti-nausea associated with balance

49
Q

phenothiazine

A

anti-nausea associated with chemicals

50
Q

ondansetron

A

anti-nausea associated with chemicals and anti-vagal

51
Q

disulfiram

A

helps chronic alcoholism; inhibits aldehyde dehydrogenase, so causes acute reactions to alcohol

52
Q

clopidogrel

A

anti-platelet agent requiring 2C9 activation

53
Q

aspart

A

fast-acting insulin

54
Q

lispro

A

fast-acting insulin

55
Q

glulisine

A

fast-acting insulin

56
Q

NPH insulin

A

intermediate-insulin

57
Q

detemir

A

long-acting insulin

58
Q

glargine

A

long-acting insulin

59
Q

glyburide

A

sulfonylurea

60
Q

glimepride

A

sulfonylurea

61
Q

repaglinide

A

meglitinide

62
Q

propanolol

A

beta-blocker; can potentiate hypoglycemia effects of sulfonylureas and meglitinides

63
Q

pioglitazone

A

thiazolidinedione

64
Q

rosiglitazone

A

thiazolidinedione

65
Q

exenatide

A

incretin (injected)

66
Q

januvia

A

DPP-4 inhibitor

67
Q

-gliptin

A

DPP-4 inhibitor (keeps GLP-1 functioning)

68
Q

canagliflozin

A

SGLT2 inhibitor

69
Q

acarbose

A

Glucosidase inhibitor

70
Q

-dronate

A

bisphosphonate

71
Q

denosumab

A

RANKL inhibitor

72
Q

teriparitide

A

PTH analog

73
Q

loperamide

A

anti-diarretic

Metabolism and Nutrition (7 decks)

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