Drugs

Question 1

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Class:

Answer 1

Analgesic, antipyretic

Question 2

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Description:

Answer 2

Used for pain and fever. No anti-inflammatory properties. Works on CNS to increase pain threshold. Effects heat regulating centers resulting in peripheral vasodilation, sweating, and heat dissipation

Question 3

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Onset and Duration:

Answer 3

PO onset 10-30min, duration 3-4hrs
IV onset 3-5min, duration 4-6hrs

Question 4

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Indications:

Answer 4

Fever
Mild to moderate pain

Question 5

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Contraindications:

Answer 5

Hypersensivity
Hepatic impairment
Renal impairment (long term)
Hypovolemia
Cronic alcohol use

Question 6

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Adverse reactions:

Answer 6

Nausea/ vomiting
Rash
Headache
Anemia
Thrombocytopenia (Low platelet count)

Question 7

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Drug interactions:

Answer 7

Avoid use with ethanol, isoniazid, OTC drugs containing acetaminophen

Question 8

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
How Supplied:

Answer 8

Capsule: 235mg, 500mg
Tablet: 325mg, 500mg, 650mg
Suspensions: 20mg/5ml, 160mg/5ml
Solution: 160mg/5ml, 500mg/15ml

Question 9

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Dose and administration:

Answer 9

Adult 50kg+
PO: 325-1000mg every 4-6hr max 4000mg per day
Infant/ Child: 10-15mh/kg 4-6hrs

Adult 50kg+
IV: 1000mg 6hrs, 650mg 4hr, max daily 4000mg
-50kg
15mg/kg 6hr, 12.5mg/kg 4hr max daily 75mg/kgn

Question 10

Acetaminophen (Tylenol),
IV Acetaminophen (Ofirmev)
Special Considerations:

Answer 10

Pregnancy: Limited risk to fetus if used short term

Harmless at low doses, Hepatotoxic if OD, Cronic dosage can decrease renal/ hepatic function