Drugs Flashcards
1
Q
Basiliximab MOA and use
A
anti-CD25 (alpha chain of IL2 receptor)
Inhibits T cell proliferation
Used for allograph rejection prophylaxis
2
Q
Abatacept MOA and use
A
Anti-CTLA4-Ig fusion protein, reduces co-stimulation of cells via CD28
Rheumatoid arthritis
3
Q
IBD
A
Vedolizumab
4
Q
Relapse remitting MS or crohns
A
Natalizumab
5
Q
Tocilizumab
A
RA
Castleman’s disease (benign proliferation in lymph tissue)
6
Q
Muromonab-CD3
A
Active allograft transplant rejection
7
Q
Anti thymocyte globulin
A
Allograft rejection (renal, heart)
8
Q
Daclizumab
A
Organ transplant rejection prophylaxis
