- Antibiotic/ antibacterial - Doesn’t easily absorbed in the acidic environment of the stomach that’s why K and Na is being added to increase its absorption. (e.g., Pen K, Pen Na)

- Lipid soluble (weak acid) (can easily pass the cell membrane). - NSAID (Non Steroidal Anti Inflammatory Drug) - Analgesic and Antipyretic - Both anti-inflammatory and anti-platelet action (causes dilution of blood) - Typically for patients that are post MI (e.g., heart attack) and post PCA (e.g., stroke) where blood clot happens - Thins the blood - Be very cautious when giving aspirin to children as they could acquire Reye’s Syndrome, an acute hepatic encephalopathy which liver and brain would be affected. - There is no aspirin that is parenteral or in any other route, aspirins are only per orem or oral drug. - Has short half life ; Half-life is 3 hours

- Has high first pass - No oral drug - Local anesthetic/ anesthesia - Has an anesthetic effect to the heart - For some heart problems, specifically heart rhythm problems or heart arrhythmias

- Has high first pass - No oral drug - For angina (chest pain that can possibly lead to heart attack) - For lowering blood pressure

- Narcotic Analgesic - Potent - For severe pain (opioid analgesics) - Addictive - Has first-pass effect - Passes to the liver first - metabolized first before it reaches the bloodstream.

- Anticoagulant (prevents blood clot) - Has first-pass effect - Passes to the liver first - metabolized first before it reaches the bloodstream. - Has 99% protein binding ability / Highly protein bound

- Anti-anxiety - Affects the nervous system (depresses, relaxes) - For people who have anxiety or depression - Has 98% protein binding ability - Highly protein bound

- Has 98% protein binding ability - NSAID - Highly protein bound - Has short half life - 2 hours half life

- Antipsychotic - Has 97% protein binding ability - Highly protein bound

- Antibiotic - Has 95% protein binding ability - Highly protein bound

- Diuretic - Has 95% protein binding ability - Highly protein bound

- Anti-anxiety - Has 92% protein binding abilit

Drugs Flashcards by HELEINA JANE BINUNGCAL

PARACETAMOL

Analgesic: Mild to moderate pain (non-opioid analgesics)
Antipyretic: Lower down temperature/ relieve fever

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PENICILLIN

Antibiotic/ antibacterial
Doesn’t easily absorbed in the acidic environment of the stomach that’s why K and Na is being added to increase its absorption. (e.g., Pen K, Pen Na)

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ASPIRIN

Lipid soluble (weak acid) (can easily pass the cell membrane).
NSAID (Non Steroidal Anti Inflammatory Drug)
Analgesic and Antipyretic
Both anti-inflammatory and anti-platelet action (causes dilution of blood)
Typically for patients that are post MI (e.g., heart attack) and post PCA (e.g., stroke) where blood clot happens
Thins the blood
Be very cautious when giving aspirin to children as they could acquire Reye’s Syndrome, an acute hepatic encephalopathy which liver and brain would be affected.
There is no aspirin that is parenteral or in any other route, aspirins are only per orem or oral drug.
Has short half life ; Half-life is 3 hours

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LIDOCAINE

Has high first pass
No oral drug
Local anesthetic/ anesthesia
Has an anesthetic effect to the heart
For some heart problems, specifically heart rhythm problems or heart arrhythmias

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SOME NITROGLYCERINES

Has high first pass
No oral drug
For angina (chest pain that can possibly lead to heart attack)
For lowering blood pressure

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MORPHINE

Narcotic Analgesic
Potent
For severe pain (opioid analgesics)
Addictive
Has first-pass effect
Passes to the liver first
metabolized first before it reaches the bloodstream.

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WARFARIN

Anticoagulant (prevents blood clot)
Has first-pass effect
Passes to the liver first
metabolized first before it reaches the bloodstream.
Has 99% protein binding ability / Highly protein bound

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PIROXICAM
- NSAID
- Has 99% protein binding ability /Highly protein bound

NSAID
Has 99% protein binding ability /Highly protein bound

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DIAZEPAM

Anti-anxiety
Affects the nervous system (depresses, relaxes)
For people who have anxiety or depression
Has 98% protein binding ability
Highly protein bound

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IBUPROFEN

Has 98% protein binding ability
NSAID
Highly protein bound
Has short half life
2 hours half life

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AMITRIPTYLINE

Antipsychotic
Has 97% protein binding ability
Highly protein bound

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CHLORPROMAZINE/ THORAZINE

Antipsychotic in the brain
Regulates the neurotransmitters
Has 95% protein binding ability
Highly protein bound
Non-selective

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DICLOXACILLIN

Antibiotic
Has 95% protein binding ability
Highly protein bound

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FUROSEMIDE

Diuretic
Has 95% protein binding ability
Highly protein bound

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LORAZEPAM

Anti-anxiety
Has 92% protein binding abilit

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PROPRANOLOL

Anti-hypertensive
Has 92% protein binding ability
Highly protein bound

VALPROIC ACID

Anti-seizure
Has 92% protein binding ability
Highly protein bound

PHENYTOIN

Anti-seizure
Long half life
22 hours half life

DIGOXIN

Cardiac glycoside
For congestive heart failure
Long half life
36 hours half life
Low therapeutic index
Loading dose

DIPHENHYDRAMINE

For allergy, but causes drowsiness

EPINEPHRINE

A nervous system drug
Stimulates alpha 1, beta 1, beta 2 (receptors of the brain or the nervous system)
An agonist

CIMETIDINE

An antagonist
Histamine 2 blocker or H2 blocker
Blocks histamine that decreases gastric acid secretion (can be used for ulcer)

BETHANECOL

A nervous system drug
Stimulates the cholinergic (parasympathetic nervous system) receptors
For urinary retention
Cholinergic might cause breathing difficulty as it constricts bronchioles
Decreases BP & HR, pupil & bronchioles constriction, increases gastric acid

AMINOGLYCOCIDES ANTIBIOTICS

Amikacin, Gentamycin, Tobramycin
Low therapeutic index

MGSO4 (Magnesium Sulfate)

* Anti-convulsant * Low therapeutic index

CAPTOPRIL

* Angiotensin-converting enzyme (ACE) inhibitor * Anti-hypertensive drug * Pharmacogenetic

ENALAPRIL

* Angiotensin-converting enzyme (ACE) inhibitor * Anti-hypertensive drug * Pharmacogenetic

FUROSEMIDE

* Diuretic * Lowers the blood volume, blood pressure * In giving this drug, check the BP first.