Drugs Flashcards

1
Q

PARACETAMOL

A

Analgesic: Mild to moderate pain (non-opioid analgesics)
Antipyretic: Lower down temperature/ relieve fever

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2
Q

PENICILLIN

A
  • Antibiotic/ antibacterial
  • Doesn’t easily absorbed in the acidic environment of the stomach that’s why K and Na is being added to increase its absorption. (e.g., Pen K, Pen Na)
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3
Q

ASPIRIN

A
  • Lipid soluble (weak acid) (can easily pass the cell membrane).
  • NSAID (Non Steroidal Anti Inflammatory Drug)
  • Analgesic and Antipyretic
  • Both anti-inflammatory and anti-platelet action (causes dilution of blood)
  • Typically for patients that are post MI (e.g., heart attack) and post PCA (e.g., stroke) where blood clot happens
  • Thins the blood
  • Be very cautious when giving aspirin to children as they could acquire Reye’s Syndrome, an acute hepatic encephalopathy which liver and brain would be affected.
  • There is no aspirin that is parenteral or in any other route, aspirins are only per orem or oral drug.
  • Has short half life ; Half-life is 3 hours
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4
Q

LIDOCAINE

A
  • Has high first pass
  • No oral drug
  • Local anesthetic/ anesthesia
  • Has an anesthetic effect to the heart
  • For some heart problems, specifically heart rhythm problems or heart arrhythmias
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5
Q

SOME NITROGLYCERINES

A
  • Has high first pass
  • No oral drug
  • For angina (chest pain that can possibly lead to heart attack)
  • For lowering blood pressure
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6
Q

MORPHINE

A
  • Narcotic Analgesic
  • Potent
  • For severe pain (opioid analgesics)
  • Addictive
  • Has first-pass effect
  • Passes to the liver first
  • metabolized first before it reaches the bloodstream.
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7
Q

WARFARIN

A
  • Anticoagulant (prevents blood clot)
  • Has first-pass effect
  • Passes to the liver first
  • metabolized first before it reaches the bloodstream.
  • Has 99% protein binding ability / Highly protein bound
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8
Q

PIROXICAM
- NSAID
- Has 99% protein binding ability /Highly protein bound

A
  • NSAID
  • Has 99% protein binding ability /Highly protein bound
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9
Q

DIAZEPAM

A
  • Anti-anxiety
  • Affects the nervous system (depresses, relaxes)
  • For people who have anxiety or depression
  • Has 98% protein binding ability
  • Highly protein bound
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10
Q

IBUPROFEN

A
  • Has 98% protein binding ability
  • NSAID
  • Highly protein bound
  • Has short half life
  • 2 hours half life
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11
Q

AMITRIPTYLINE

A
  • Antipsychotic
  • Has 97% protein binding ability
  • Highly protein bound
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12
Q

CHLORPROMAZINE/ THORAZINE

A
  • Antipsychotic in the brain
  • Regulates the neurotransmitters
  • Has 95% protein binding ability
  • Highly protein bound
  • Non-selective
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13
Q

DICLOXACILLIN

A
  • Antibiotic
  • Has 95% protein binding ability
  • Highly protein bound
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14
Q

FUROSEMIDE

A
  • Diuretic
  • Has 95% protein binding ability
  • Highly protein bound
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15
Q

LORAZEPAM

A
  • Anti-anxiety
  • Has 92% protein binding abilit
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16
Q

PROPRANOLOL

A
  • Anti-hypertensive
  • Has 92% protein binding ability
  • Highly protein bound
17
Q

VALPROIC ACID

A
  • Anti-seizure
  • Has 92% protein binding ability
  • Highly protein bound
17
Q

PHENYTOIN

A
  • Anti-seizure
  • Long half life
  • 22 hours half life
18
Q

DIGOXIN

A
  • Cardiac glycoside
  • For congestive heart failure
  • Long half life
  • 36 hours half life
  • Low therapeutic index
  • Loading dose
19
Q

DIPHENHYDRAMINE

A

For allergy, but causes drowsiness

20
Q

EPINEPHRINE

A
  • A nervous system drug
  • Stimulates alpha 1, beta 1, beta 2 (receptors of the brain or the nervous system)
  • An agonist
21
Q

CIMETIDINE

A
  • An antagonist
  • Histamine 2 blocker or H2 blocker
  • Blocks histamine that decreases gastric acid secretion (can be used for ulcer)
22
Q

BETHANECOL

A
  • A nervous system drug
  • Stimulates the cholinergic (parasympathetic nervous system) receptors
  • For urinary retention
  • Cholinergic might cause breathing difficulty as it constricts bronchioles
  • Decreases BP & HR, pupil & bronchioles constriction, increases gastric acid
23
Q

AMINOGLYCOCIDES ANTIBIOTICS

A
  • Amikacin, Gentamycin, Tobramycin
  • Low therapeutic index
24
Q

MGSO4 (Magnesium Sulfate)

A
  • Anti-convulsant
  • Low therapeutic index
25
Q

CAPTOPRIL

A
  • Angiotensin-converting enzyme (ACE) inhibitor
  • Anti-hypertensive drug
  • Pharmacogenetic
26
Q

ENALAPRIL

A
  • Angiotensin-converting enzyme (ACE) inhibitor
  • Anti-hypertensive drug
  • Pharmacogenetic
27
Q

FUROSEMIDE

A
  • Diuretic
  • Lowers the blood volume, blood pressure
  • In giving this drug, check the BP first.