Drugs Flashcards
What is salbutamol?
B2 receptor agonist
What is terbutaline?
B2 receptor agonist
What is salmeterol?
Long acting B2 receptor agonist
What is formoterol?
Long acting B2 receptor agonist
What is ipratropium?
Antimuscurinic
What is tiotropium?
Antimuscurinic
What is theophylline?
Xanthine
What is aminiophylline?
Xanthine
What do B2 receptor antagonists do?
Block sympathetic nervous system action on B2 receptors, cauing bronchial dilation
What do antimuscurinics do?
Block parasympathetic nervous system actions on muscurinic receptors, stopping bronchial constriction
What are indications of B2 receptor agonists?
Asthma
COPD
What are indications for anti-muscurinics?
Chronic asthma (stage 4)
COPD (symptomatic relief)
SHOULD NOT BE USED ALONE
What do xanthines do?
Cause bronchodilation
How is theophylline administered?
Oral
How is aminophylline administered?
Slow IV infusion
What are indications for xanthines?
Asthma (3rd line drug)
COPD
What is beclometasone?
Corticosteroid
What is budesonide?
Corticosteroid
What is prednisolone?
Corticosteroid
How is beclometasone administered?
Inhaled
How is budesonide administered?
Inhaled
How is prednisolone administered?
Oral
What do corticosteroids do?
Reduce inflammatory response in airways
Reduce oedema and mucus production in airways
Inhibit allergic reactions
What are indications for inhaled corticosteroids?
Stage 2 asthma
COPD (in combination with Leukotreine antagonist)
Hayfever
What are indications for oral corticosteroids?
Acute exacerbations of asthma/COPD
What is motelukast?
Leukatriene receptor antagonist
What is zafirlukast?
Leukotreine receptor antagonist
What do leukotreine receptor antagonists do?
Block effects of leukotrienes at receptors in the airways which decreases the early and late responses to allergens
Reduce bronchoconstriction, inflammation and mucus production
What are indications for leukatriene receptor antagonists?
Prophylaxis for non-acute asthma
What is rifampcin?
TB therapy
What is isoniazid?
TB therapy
What is ethambutol?
TB therapy
What is pyrazinamide?
TB therapy
What is the treatment plan for TB?
All 4 TB drugs for 2 months
Then rifampicin and issoniazide for a further 4 months
What are side effects of rifampicin?
Orange irn bru tears/urine
Induces liver enzymes
Hepatitis
What are side effects of isoniazid?
Hepatitis
Peripheral neuropathy
What are side effects of ethambutol?
Optic neuropathy
What are side effects of pyrazinamide?
Gout