Drugs Flashcards

1
Q

Cardiac glycoside for CHF

A

Digoxin

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2
Q

Suppresses intracellular potassium

A

Digoxin

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3
Q

Digoxin at 3 ng/mL

A

Decrease ventricular depolarization, tachycardia

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4
Q

Half life for Digoxin

A

38 hours

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5
Q

Peak concentration of Digoxin

A

8-10 hours after oral dose

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6
Q

Propranolol halflife and toxic level?

A

3 hours and >100ng/mL

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7
Q

Digitoxin H and T

A

4-6 hours and greater than 25 ng/mL

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8
Q

Once Digoxin is metabolized in the liver, product is

A

Digitoxin

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9
Q

Elimination of Quinidine

A

Metabolism in the liver

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10
Q

Treatment of Quinidine

A

To treat cardiac arrhythmia

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11
Q

2 Most Common Fomulation

A

Quinidine sulfate and gluconate

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12
Q

Peak concentration of Quinidine Sulfate

A

2 hours after

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13
Q

Peak of Quinidine gluconate

A

4-5 hours after

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14
Q

Trough of Quinidine gluconate

A

1 hour after

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15
Q

Half life of Quinidine

A

5-12 hours

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16
Q

Active metabolite of quinidine

A

N acetylprocainamide

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17
Q

Metabolism of quinidine happens in liver through

A

Acetylation

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18
Q

Procainamide H and T

A

3-5 hours and 4-10ng/mL

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19
Q

Peak Procainamide

A

1 hour after intake

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20
Q

Used to treat cardiac arrhythmias

A

Procainamide

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21
Q

Another drug for cardiac arrhythmia with peak 1-2 hours after dose

A

Disopyramide

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22
Q

Not bound to proteins drug

A

Lidocaine

23
Q

Lidocain H and T

A

2 hours and above 5.5

24
Q

Local anesthetic substance

A

Lidocaine

25
Q

Undergoes metabolism in liver through

A

dealkylation

26
Q

Used to treat gram negative bacteria

A

Aminoglycosides

27
Q

4 aminoglycosides

A

Gentamicin, tobramycin, amikacin, kanamycin

28
Q

Administration route for Aminoglycosides

A

IM or IV

29
Q

Elimination of aminoglycosides

A

Renal filtration

30
Q

Toxic effects of Aminoglycosides

A

Ototoxicity and Nephrotoxicity

31
Q

Treatment of gram positive bacteria

A

Vancomycin

32
Q

Toxic effect of Vancomycin

A

Red man syndrome

33
Q

Method of Vancomycin

A

Chromatography and Immunoassays

34
Q

Specimen of Anticonvulsants

A

Trough serum concentration

35
Q

Stabilizes the neuronal membranes

A

Phenobarbital

36
Q

Block Na and Ca influx into neurons

A

Phenytoin

37
Q

Other name for Phenytoin

A

Dilantin

38
Q

Injectable form of phenytoin

A

Fosphenytoin

39
Q

Anemia and Hypoalbuminemia

A

Phenytoin

40
Q

Enhances GABA mediated inhibitory system

A

Valproic acid

41
Q

Other name for Valproic acid

A

Depakene

42
Q

Treatment for petit mal

A

Valproic acid

43
Q

Acts by decreasing motor cortex activity

A

Ethosuximide

44
Q

Other name for ethosuximide

A

Zarontin

45
Q

Children with Lennox Gastaut Syndrome

A

Felbamate

46
Q

Inhibitor of Lamotrigine

A

Valproic Acid

47
Q

Indications: partial and generalizes seizures

A

Lamotrigine, Levetiracetam, Topiramate, Zonisamide

48
Q

Mono therapy or together with AEDs for complex partial seizures

A

Gabapentin

49
Q

Indications of mono therapy of practical seizures and in tonic clonic seizures

A

Oxcarbazepine

50
Q

Treatment for partial seizuees

A

Tiagabine

51
Q

Side effect: parasthesia

A

Tiagabine

52
Q

Pins and needles sensation

A

Topiramate

53
Q

Proform of phenobarbital

A

Primidone

54
Q

Carbamazepine, other term

A

Tegretol