Drugs Flashcards
Cardiac glycoside for CHF
Digoxin
Suppresses intracellular potassium
Digoxin
Digoxin at 3 ng/mL
Decrease ventricular depolarization, tachycardia
Half life for Digoxin
38 hours
Peak concentration of Digoxin
8-10 hours after oral dose
Propranolol halflife and toxic level?
3 hours and >100ng/mL
Digitoxin H and T
4-6 hours and greater than 25 ng/mL
Once Digoxin is metabolized in the liver, product is
Digitoxin
Elimination of Quinidine
Metabolism in the liver
Treatment of Quinidine
To treat cardiac arrhythmia
2 Most Common Fomulation
Quinidine sulfate and gluconate
Peak concentration of Quinidine Sulfate
2 hours after
Peak of Quinidine gluconate
4-5 hours after
Trough of Quinidine gluconate
1 hour after
Half life of Quinidine
5-12 hours
Active metabolite of quinidine
N acetylprocainamide
Metabolism of quinidine happens in liver through
Acetylation
Procainamide H and T
3-5 hours and 4-10ng/mL
Peak Procainamide
1 hour after intake
Used to treat cardiac arrhythmias
Procainamide
Another drug for cardiac arrhythmia with peak 1-2 hours after dose
Disopyramide