Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Schizophrenia > Drug Treatments > Flashcards

Drug Treatments Flashcards

1
Q

What are atypical antipsychotics used to treat?

A

Positive symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Give an example of a typical antipsychotic

A

Chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are atypical drugs used to treat?

A

Positive and negative symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Give an example of an atypical antipsychotic

A

Clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe how TYPICAL antipsychotic drugs work

A

Typical antipsychotics are used to treat positive symptoms in SZ such as Hallunications. They were the original antipsychotics and are conventional, first generation drugs. They do this by working as dopamine antagonists so they block receptors- particularly D2 receptors but do not stimulate dopamine receptors. They reduce the stimulation of the dopamine system in the Mesolimbic dopamine lath way

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe how atypical antipsychotic drugs work

A

Second generation antipsychotics were made in order to prevent as serious extrapyramidenal side effects. They work by temporarily blocking the D2 receptors and the dissociate to allow normal dopamine transmission. They also have an effect on serotonin- with serotonin also being an inhibitory nerve.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When was dopamine disocovered?

A

1952

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What study supports the effectiveness of antipsychotics?

A

Leucht et al (2002)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What did Leucht et al find?

A

In a meta analysis of 65 studies involving 6,000 patients/ all were stabilised but some had been taken off an went on a placebo/ after 12 months 67% of those on placebo replaced come pared to 27%?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a weakness of typical antipsychotics?

A

The extrapyramidal side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Why do extrapyramidal side effects occur?

A

Can impact the teas of the brain that in involve in motor activity/ similar to symptoms of Parkinson’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What other side effects can patients experience long term wise with typical antipsychotics?

A

Taridive dyskinesia- involuntary movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What can happen as a result of side effects?

A

Patients stop taking medication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What did Crossley et al find?

How many studies were in their meta analysis?

A

15 studies/ no difference in terms of side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a weakness of antipshcitocs in general?

A

Can have motivational deficits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Who argued that antipsychotics can have motivational deficits and why?

A

Ross and Read believe it reinforces the view that there is something wrong with the patient/ prevents patient form changing lifestyle which could lead to continuous relapse

17
Q

Why is it bad that antipshcitocs don’t deal with environmental issues?

A

They don’t work to stop stressors, therapy can prevent relapse so a combination may be best as that may take a more holistic approach as giving drugs means that you’re reducing the complicated illness to Biological reasons

18
Q

What study supports the effectiveness of antipsychotics?

A

Leucht et al (2002)

19
Q

What did Leucht et al find?

A

In a meta analysis of 65 studies involving 6,000 patients/ all were stabilised but some had been taken off an went on a placebo/ after 12 months 67% of those on placebo replaced come pared to 27%?

20
Q

What is a weakness of typical antipsychotics?

A

The extrapyramidal side effects

21
Q

Why do extrapyramidal side effects occur?

A

Can impact the teas of the brain that in involve in motor activity/ similar to symptoms of Parkinson’s

22
Q

What other side effects can patients experience long term wise with typical antipsychotics?

A

Taridive dyskinesia- involuntary movements

23
Q

What can happen as a result of side effects?

A

Patients stop taking medication

24
Q

What did Crossley et al find?

How many studies were in their meta analysis?

A

15 studies/ no difference in terms of side effects

25
Q

What is a weakness of antipshcitocs in general?

A

Can have motivational deficits

26
Q

Who argued that antipsychotics can have motivational deficits and why?

A

Ross and Read believe it reinforces the view that there is something wrong with the patient/ prevents patient form changing lifestyle which could lead to continuous relapse

27
Q

Why is it bad that antipshcitocs don’t deal with environmental issues?

A

They don’t work to stop stressors, therapy can prevent relapse so a combination may be best as that may take a more holistic approach as giving drugs means that you’re reducing the complicated illness to Biological reasons

Schizophrenia (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions