drug therapy for tx of infection pt3 viral/ viruses Flashcards

1
Q

drug therapy for viral infection

A

vaccines and antiviral agents

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2
Q

viruses can cause variety of symptoms such as

A

warts, common cold, flu, chickenpox, covid19, measles, mumps, monkeypox, HIV, HPV, hepatitis

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3
Q

viruses are

A

intracellular so they must be able to enter the host cell to cause damage

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4
Q

viral viruses will normally

A

go away on own, antibiotic do not treat viral only bacterial

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5
Q

common symptoms of viruses and viral infections

A

fever, headache, cough, malaise, muscle aches, N,V,D, insomnia, photophobia

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6
Q

herpes viruses

A

herpes simplex (cold sores HSV-1, genital sores HSV-2), chickenpox (herpes varicella), shingles (herpes zoster), cytomegalovirus (CMV)

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7
Q

drugs for herpesvirus infections (antivirals): herpes simplex & varicella-zoster

A

topicals: docosanol (OTC), penciclovir, trifluridine/ systemics (stop help the spread): famciclovir, acyclovir, valacyclovir / prevents viral replication (does not cure/ less time in-between outbreaks)

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8
Q

drugs for herpesvirus infections (antivirals): herpes simplex & varicella-zoster (FAV): adverse effects

A

CNS effects (malaise & fatigue), bone marrow suppression (anemia), skin effects (rash bc decrease in platelets), renal effects (hemolytic uremic)

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9
Q

drugs for herpesvirus infections (antivirals): herpes simplex & varicella-zoster: cautions

A

renal dysfunction, CNS disorders, use caution in neonates/ infants & children

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10
Q

hemolytic uremic syndrome symptoms

A

pallor, fatigue, blood in urine & stool

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11
Q

pt education on drugs for herpesvirus infections (antivirals): herpes simplex & varicella-zoster (FAV):

A

tx of initial infection is longer than recurrence/ herpes is never cured and can spread even when dormant

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12
Q

cytomegalovirus affects the

A

eyes (blurry), respiratory tract, liver (hepatitis)

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13
Q

cytomegalovirus seen in

A

pts that are immunocompromised (common in HIV pts)

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14
Q

drugs for cytomegalovirus

A

ganciclovir (PO, IV, topical)

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15
Q

nursing considerations when using ganciclovir

A

monitor BUN/ creatinine, CBC/ pregnancy test before and 3 months after

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16
Q

adverse effects of ganciclovir

A

CNS (fever, chills) / Skin (itching from head to toe)/ Renal effects (increase of BUN & creatinine), black box warning (cause bone marrow suppression & causes birth defects)

17
Q

contraindication for glanciclovir

A

pregnancy/ lactating, bone marrow suppression (leading to anemias)/(pts receiving chemo), renal dysfunction

18
Q

drugs for respiratory syncytial virus (RSV)/ influenza (flu) examples

A

oseltamivir (tamiflu) for flu (give in the first 48 hours), ribavirin (RSV)

19
Q

black box warning for ribavirin

A

tetrogenic (if trying to get pregnant or are pregnant, you can not be in the room with the child receiving treatment)

20
Q

drugs to treat Hep B

A

nucleoside analogs: black box warning causing lactic acidosis & hepatomegaly (liver in enlarged with fatty deposits) RUQ pain & jaundice

21
Q

adverse effects of drugs to treat Heb B

A

black box warning causing lactic acidosis & hepatomegaly (liver in enlarged with fatty deposits) RUQ pain & jaundice, pancreatitis, fever, vomiting, tachycardia

22
Q

drugs to treat Heb C

A

pegylated interferon

23
Q

HIV attacks

A

T cells & immune cells (CD4 specific cells)

24
Q

drugs to treat HIV

A

antiretroviral treatment (ART)

25
Q

patient education for viral hepatitis and HIV treatment

A

prevent transmission (want CD4 < 400), adhere to treatment regimen, regular blood tests (CBC, CD4, kidney/ liver function), practice safe sex, use clean needles

26
Q

what can you give to help treat covid

A

monoclonal antibodies, remdesivir (given IV)

27
Q

which of the following is true regarding oseltamivir

A

the drug should be started within the first 48 hours