Drug therapy Flashcards
3 assumptions of drug therapy?
Medical model of illness
Behaviour is determined by neurotransmitters
Behaviour is determined by localisation of briain function
Medical model of illness
psychological disorders, have a biological cause. medical illnesses are like physical illness and so can be treated in a physical way.
Therefore, these illnesses can be treated in a physical way using drug therapies.
Neurotransmitters
Low levels of serotonin have been linked to depression. High levels of dopamine have been linked to schizophrenia.
Drugs can be used to increase or block the action of neurotransmitters in the brain which will alter our mood, thoughts and actions.
localisation of brain function
Different areas of the brain are responsible for different functions.
We can use drugs to target specific regions of the brain to treat mental illnesses such as anxiety, depression and schizophrenia.
3 components of drug therapy
antidepressants
antipsychotics
antianxiety
Antipsychotic drugs
used to treat psychotic mental disorders such as schizophrenia
Whats a psychotic illness
a person with a psychotic illness such as schizophrenia, has lost touch with reality and has little insight into their condition.
Symptoms of schizophrenia
Positive: an addition, the presence of symptoms (delusions, hallucinations, hearing voices)
Negative symptoms: an absence, or lack of normal function (flattened affect, reduced speech, lack of motivation)
What are the 2 types of antipsychotic drugs?
Conventional antipsychotics: treat positive symptoms of schizophrenia. They block the action of dopamine neurotransmitters binding to (but not stimulating) dopamine receptors.
Atypical antipsychotics: treat positive and negative symptoms of schizophrenia.
They temporarily bind to dopamine receptors and then rapidly dissociate (separate) allowing normal dopamine transmission. They have fewer side effects than conventional antipsychotics. (eg, clozaril)
What are antidepressants?
Treat depression
Symptoms of depression
Low mood, changes in appetite
Whats reuptake?
In neurotypical brains, neurotransmitters are constantly being released from the presynaptic neuron to stimulate the postsynaptic neuron. To terminate their action, neurotransmitters are reabsorbed back into the presynaptic neuron and are broken down by an enzyme.
Types of antidepressants
SSRI: Selective seortonin reuptake inhibitors
They bind onto the presynaptic neuron so that serotonin cannot be reabsorbed. This increases the amount of serotonin in the synapse, prolonging its activity which can be received by the postsynaptic neuron.
What do antianxiety drugs do
treat anxiety and stress
biological cause of anxiety?
low levels of GABA (a neurotransmitter that slows down the activity of the central nervous system).
High levels of adrenaline and noradrenaline which are part of the fight or flight response.