Drug Resources Flashcards
Package inserts (PIs):
1. What info is found in PIs?
2. Where can PIs be accessed?
3. Who approves PIs?
- -Recent major changes/dates
-Indications, usages, dosing, ROAs
-MOA, pharmacology
-AVEs, Warnings, CIs, BBW
-DDIs
-Overdose/toxicology
-Use in specific populations
-Drug abuse/dependence
-Others: inactive ingredients, PK/PD, clinical studies, how supplied, storage/handling, pt counseling information
2.
-Online: DailyMed (NLM), Drugs@FDA, Drug Manufacturer’s website
-Printed: attached to box/bottle of product
- FDA
Resources with drug monographs for general drug information:
-Which ones are free?
-What are the resources drug monographs use?
Drug monographs are based on package inserts and other sources such as new clinical studies
Not-paid: Drugs.com, RxList
Drug monograph databases (contain additional information such as IV drug compatibility, drug class comparisons, natural products, drug identification, and international drug names):
-Clinical Pharmacology
-Facts and Comparisons
-Lexicomp
-Micromedex
American Hospital Formulary Service (AHFS): have lots of supporting evidence and references
What is the Pharmacist’s Letter?
Monthly newsletter for subscribers with short summaries on new or updated drug information with additional tools such as:
-New drug approvals, withdrawals
-New dosage forms, first-time generics
-Charts (drug class comparisons, disease-state TX summaries)
-Pt education summaries and flyers
-Continuing education (CE)
-Training materials for technicians and interns
What information does the follow resource provide: AHFS/AHFS CDI
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
AHFS = American Hospital Formulary Service
-Off label uses
-IV drug compatibility
-International drug names
What information does the follow resource provide: Clinical Pharmacology
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
Everything listed:
-Off-label uses
-IV drug compatibility
-Drug/pill identification
-Natural products
-Drug class comparisons
-Pricing
-International drug names
Everything
What information does the follow resource provide: Epocrates and Epocrates +
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
Epocrates:
-Off-label uses
-Drug/pill identification
-Natural products
-Drug class comparisons
-Pricing
Epocrates +: specifically has natural products information
Everything, but IV drug compatibility and international drug names
What information does the follow resource provide: Facts and Comparisons
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
-Off-label uses
-IV drug compatibility
-Drug/pill identification
-Natural products
-Drug class comparisons
-International drug names
Everything, but pricing
What information does the follow resource provide: Drugs.com
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
-Off-label uses
-Drug/pill identification
-Natural products
-Drug class comparisons
-Pricing
-International drug names
Everything, but IV drug compatibility
What information does the follow resource provide: Lexicomp/Micromedex
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
-Off-label uses
-IV drug compatibility
-Drug/pill identification
-Natural products
-Drug class comparisons
-Pricing
-International drug names
Everything
What information does the follow resource provide: mobilePDR
**off-label uses, IV drug compatibility, drug/pill identification, natural products, drug class comparisons, pricing, and international drug names?
ONLY provides drug/pill identification and drug class comparisons
Guidelines for: Anticoagulation
American College of Chest Physicians (CHEST guidelines)
Guidelines for: CV diseases (CVD)
American College of Cardiology / American Heart Association (ACC/AHA)
Guidelines for: Diabetes mellitus (DM)
- American Association of Clinical Endocrinologists (AACE)
- American Diabetes Association (ADA)
Guidelines for: Infectious disease
- Infectious Disease Society of American (IDSA)
- HIV/AIDs: US Dept. of Health and Human Services (clinicalinfo.hiv/gov)
- STIs: Centers for Disease Control (CDC)
Guidelines for: Oncology
- American Society of Clinical Oncology (ASCO)
- National Comprehensive Cancer Care Network (NCCN)
Guidelines for: Pediatrics
The American Academy of Pediatrics (AAP)
Guidelines for: Pregnancy / Women’s Health
The American College of Obstetricians and Gynecologists (ACOG)
Guidelines for: Psychiatric diseases
American Psychiatric Association (APA) Diagnostic and Statistical Manner of Mental Disorders 5th edition (DSM-5)
Guidelines for: Asthma
Global Initiative for Asthma (GINA)
Guidelines for: COPD
Global Initiative for COPD (GOLD)
Guidelines for: Renal
Kidney Disease Improving Global Outcomes (KDIGO)
Guidelines for: Vaccines
- Advisory Committee on Immunization Practices (ACIP)
- Centers for Disease Control (CDC)
Where to search for reported adverse reactions or where to report?
FDAable: FDA searchable database of adverse reactions caused by medicines, vaccines, devices, tobacco products, or dietary supplements
MedWatch: FDA’s Adverse Event Reporting System (FAERS)
Vaccine Adverse Event Reporting System (VAERS)
Compound and Pharmaceutics References
- Allen’s The Art, Science, and Technology of Pharmaceutical Compounding
- Safety Data Sheets (SDS)
- Merck Index (online databese for chemicals, drugs, biologics)
- Remington: The Science and Practice of Pharmacy
- USP: 795 for non-sterile, 797 for sterile, 800 for hazardous, and NF for monogrpahs/dosage forms/compounded preparations and excipients
