Drug Reactions - Name Causal Agent Flashcards

1
Q

Coronary Vasospasm

A

Cocaine, Sumatriptan, Ergot Alkaloids

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2
Q

Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, CC-blockers

“VANC”

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3
Q

Dilated Cardiomyopathy

A

Doxorubicin (Adriamycin), Daunorubicin

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4
Q

Torsades de pointes

A

Class III (Sotalol) & Class IA (Quinidine) antiarrhythmics

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5
Q

Agranulocytosis

A

Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone

“Agranulocytosis Could Certainly Cause Pretty Major Damage”

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6
Q

Aplastic anemia

A

Chloramphenicol, Benzene, NSAIDS, Propylthiouracil, Methimazole

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7
Q

Direct Coombs-positive hemolytic anemia

A

Methyldopa, Penicillin

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8
Q

Gray baby syndrome

A

Chloramphenicol

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9
Q

Hemolysis in G6PD-deficient patients

A

Isoniazid (INH), Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

“Hemolysis IS PAIN”

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10
Q

Megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs

“having a BLAST w/ PMS”

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11
Q

Thrombotic complications

A

OCPs (estrogens)

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12
Q

Cough

A

ACE-inhibitors

Note: ARBs, like Losartan = no cough

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13
Q

Pulmonary Fibrosis

A

BLeomycin, Amiodarone, Busulfan

“it’s hard to BLAB when you have pulmonary fibrosis”

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14
Q

Acute Cholestatic Hepatitis, Jaundice

A

Erythromycin

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15
Q

Focal to massive hepatic necrosis

A

Halothane, Amanita phalloides, Valproic acid, Acetaminophen

“Liver HAVAc”

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16
Q

Hepatitis

A

INH

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17
Q

Pseudomembranous Colitis

A

Clindamycin, Ampicillin

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18
Q

Adrenocortical insufficiency

A

Glucocorticoid w/drawal (HPA suppression)

19
Q

Gynecomastia

A

Spironolactone, Digitalis, Cimetidine, Alcohol (chronic use), Estrogens, Ketoconazole

“Some Drugs Create Awkward Effin’ Knockers”

20
Q

Hot flashes

A

Tamoxifen, Clomiphene

21
Q

Hyperglycemia

A

Niacin, Tacrolimus, Protease inhibitors, HCTZ, Corticosteroids

22
Q

Hypothyroidism

A

Lithium, Amiodarone, Sulfonamides

23
Q

Fat redistribution

A

Glucocorticoids, Protease inhibitors

24
Q

Gingival Hyperplasia

A

Phenytoin, Verapamil

25
Gout
Furosemide, Thiazides, Niacin, Cyclosporine
26
Myopathies
Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon-α, Penicillamine, Statins, Glucocorticoids "Finsh N CHIPS Give you myopathies"
27
Osteoporosis
Corticosteroids, Heparin
28
Photosensitivity
Sulfonamides, Amiodarone, Tetracycline "SAT for a photo"
29
Rash (SJS)
Penicillin, Ethosuximide, Caramazepine, Sulfa drugs, Lamotrigine, Allopurinol, Phenytoin, Phenobarbital "Bad rash after a PEC SLAPP"
30
SLE-like syndrome
Hydralazine, INH, Procainamide, Phenytoin "It's not HIPP to have lupus"
31
Teeth (kids)
Tetracyclines
32
Tendonitis, tendon rupture, & cartilage damage
Fluoroquinolones
33
Diabetes Insipidus
Lithium, Demeclocycline
34
Fanconi's Syndrome
Expired Tetracycline
35
Hemorrhagic Cystitis
Cyclophosphamide, Ifosfamide (prevent by coadministering w/ mesna)
36
Interstitial Nephritis
Methicillin, NSAIDS, Furosemide
37
SIADH
Carbamazepine, Cyclophosphamide
38
Cinchonism
Quinidine, Quinine
39
Parkinson-like syndrome
Antipsychotics, Reserpine, Metoclopramide
40
Seizures
Isoniazid, Bupropion, Imipenem/cilastatin, Tramadol, Enflurane, Metoclopramide "w/ seizures, I BITE My tongue"
41
Tardive dyskinesia
Antipsychotics
42
Antimuscarinic
Atropine, TCAs, H1-blockers, Neuroleptics
43
Disulfiram-like reaction
Metronidazole, certain Cephalosporins, Procarbazine, 1st generation Sulfonylureas
44
Nephrotoxicity/Ototoxicity
Aminoglycosides, Vancomycin, Loop Diuretics, Cisplatin