Drug Reactions - Name Causal Agent Flashcards
Coronary Vasospasm
Cocaine, Sumatriptan, Ergot Alkaloids
Cutaneous flushing
Vancomycin, Adenosine, Niacin, CC-blockers
“VANC”
Dilated Cardiomyopathy
Doxorubicin (Adriamycin), Daunorubicin
Torsades de pointes
Class III (Sotalol) & Class IA (Quinidine) antiarrhythmics
Agranulocytosis
Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone
“Agranulocytosis Could Certainly Cause Pretty Major Damage”
Aplastic anemia
Chloramphenicol, Benzene, NSAIDS, Propylthiouracil, Methimazole
Direct Coombs-positive hemolytic anemia
Methyldopa, Penicillin
Gray baby syndrome
Chloramphenicol
Hemolysis in G6PD-deficient patients
Isoniazid (INH), Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
“Hemolysis IS PAIN”
Megaloblastic anemia
Phenytoin, Methotrexate, Sulfa drugs
“having a BLAST w/ PMS”
Thrombotic complications
OCPs (estrogens)
Cough
ACE-inhibitors
Note: ARBs, like Losartan = no cough
Pulmonary Fibrosis
BLeomycin, Amiodarone, Busulfan
“it’s hard to BLAB when you have pulmonary fibrosis”
Acute Cholestatic Hepatitis, Jaundice
Erythromycin
Focal to massive hepatic necrosis
Halothane, Amanita phalloides, Valproic acid, Acetaminophen
“Liver HAVAc”
Hepatitis
INH
Pseudomembranous Colitis
Clindamycin, Ampicillin