Antidotes/Treatments Flashcards by Veena Katikineni

Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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Q

Salicylates

A

NaHCO3 (alkalinize urine)

Dialysis

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Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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Q

Acetylcholinesterase inhibitors (organophosphates)

A

Atropine, Pralidoxime

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Q

Antimuscarinic, Anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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Q

β-blockers

A

Glucagon

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Q

Digitalis

A

Normalize K+, Lidocaine, Anti-dig Fab, fragments, Mg(2+)

“KLAM”

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Q

Iron

A

deFEroxamine, deFErasirox

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Q

Lead

A

CaEDTA, Dimercaprol, Succimer, Penicillamine

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Q

Mercury

A

Dimercaprol (BAL), Succimer

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Q

Arsenic

A

Dimercaprol (BAL), Succimer, Penicillamine

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Q

Gold

A

Dimercaprol (BAL), Succimer, Penicillamine

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Q

Copper

A

Penicillamine

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Q

Cyanide

A

Nitrite + Thiosulfate, Hydroxocobalamin

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Q

Methemoglobin

A

Methylene blue, vitamin C

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Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

Q

Opioids

A

Naloxone/naltrexone

Q

Benzodiazepines

A

Flumazenil

Q

TCAs

A

NaHCO3 (plasma alkalinization)

Q

Heparin

A

Protamine

Q

Warfarin

A

Vitamin K, fresh frozen plasma

Q

tPA

A

Aminocaproic acid

Q

Streptokinase

A

Aminocaproic acid

Q

Urokinase

A

Aminocaproic acid

Q

Theophylline

A

β-blocker

Q

Rat poison (Brodifacoum)

A

Fresh Frozen Plasma