Drug reactions Flashcards

1
Q

Adrenocortical insufficiency

A

HPA suppression secondary to glucocorticoid withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Hot flashes

A
  • Tamoxifen

- Clomiphene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hyperglycemia

A
  • Tacrolimus
  • Protease inhibitors
  • Niacin
  • HCTZ
  • Corticosteroids

“Taking Pills Necessitates Having blood Checked”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hypothyroidism

A
  • Lithium
  • Amiodarone
  • Sulfonamides
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acute cholestatic hepatitis, jaundice

A

Erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Diarrhea

A
  • Acamprosate
  • Acarbose
  • Cholinesterase inhibitors
  • Colchicine
  • Erythromycin
  • Ezetimibe
  • Metformin
  • Misoprostol
  • Orlistat
  • Pramlintide
  • Quinidine
  • SSRIs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Focal to massive hepatic necrosis

A
  • Halothane
  • Amanita phalloides (death cap mushroom)
  • Valproic acid
  • Acetaminophen

Liver “HAVAc”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Hepatitis

A
  • Rifampin
  • Isoniazid
  • Pyrazinamide
  • Statins
  • Fibrates
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pancreatitis

A
  • Didanosine
  • Corticosteroids
  • Alcohol
  • Valproic acid
  • Azathioprine
  • Diuretics (furosemide, HCTZ

“Drugs Causing A Violent Abdominal Distress”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pill-induced esophagitis

A
  • Tetracyclines
  • Bisphosphonates
  • Potassium chloride

Caustic effect minimized with upright posture and adequate water ingestion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pseudomembrarnous colitis

A
  • Clindamycin
  • Ampicillin
  • Cephalosporins

Antibiotics predispose to superinfection by resistant C difficile

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Agranulocytosis

A
  • Clozapine
  • Carbamazepine
  • Propylthiouracil
  • Methicmazole
  • Colchicine
  • Ganciclovir

“Can Cause Pretty Major Collapse of Granulocytes”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Aplastic anemia

A
  • Carbamazepine
  • Methimazole
  • NSAIDs
  • Benzene
  • Chloramphenicol
  • Propylthiouracil

“Can’t Make New Blood Cells Properly”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Direct Coombs-positive hemolytic anemia

A
  • Methyldopa

- Penicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Gray baby syndrome

A

Chloramphenicol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hemolysis in G6PD deficiency

A
  • Isoniazid
  • Sulfonamides
  • Dapsone
  • Primaquine
  • Aspirin
  • Ibuprofen
  • Nitrofurantoin

“Hemolysis IS D PAIN”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Megaloblastic anemia

A
  • Phenytoin
  • Methotrexate
  • Sulfa drugs

“Having a BLAST with PMS”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Thrombocytopenia

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Thrombotic complications

A
  • OCPs

- Hormone replacement therapy

20
Q

Fat redistribution

A
  • Protease inhibitors
  • Glucocorticoids

“Fat PiG”

21
Q

Gingival hyperplasia

A
  • Phenytoin
  • Ca2+ channel blockers
  • Cyclosporine

“Painful Tophi and Feet Need Care”

22
Q

Hyperuricemia (gout)

A
  • Pyrizinamide
  • Thiazides
  • Furosemides
  • Niacin
  • Cyclosporine
23
Q

Myopathy

A
  • Fibrates
  • Niacin
  • Colchicine
  • Hydroxychloroquine
  • Interferon alpha
  • Penicillamine
  • Statins
  • Glucocorticoids
24
Q

Osteoporosis

A
  • Glucocorticoids

- Heparin

25
Photosensitivity
- Sulfonamides - Amiodarone - Tetracyclines - 5-FU "SAT For Photo"
26
Rash (SJS)
- Anti-epileptic drugs (especially lamotrigine) - Allopurinol - Sulfa drugs - Penicillin "Steven Johnson has epileptic allergy to sulfa drugs and penicillin"
27
SLE-like syndrome
- Sulfa drugs - Hydralazine - Isoniazid - Procainamide - Phenytoin - Etanercept Having lupus is "SHIPP-E"
28
Teeth discoloration
Tetracyclines
29
Tendonitis, tendon rupture and cartilage damage
Fluroquinolones
30
Cinchonism
- Quinidine | - Quinine
31
Parkinson-like syndrome
- Anti-psychotics - Reserpine - Metoclopramide "Cogwheel rigidity of ARM"
32
Seizures
- Isoniazid (vitamin B6 deficiency) - Bupropion - Imipenem/cilastatin - Tramadol - Enflurane "With seizures, I BITE my tongue"
33
Tardive dyskinesia
- Anti-psychotics | - Metoclopramide
34
Diabetes insipidus
- Lithium | - Demeclocycline
35
Fanconi syndrome
- Tenofovir | - Isofosfamide
36
Hemorrhagic cystitis
- Cyclophosphamide | - Isofosfamide
37
Interstitial nephritis
- Methicillin - NSAIDs - Furosemide
38
SIADH
- Carbamazepine - Cyclophosphamide - SSRIs "Can't Concentrate Serum Sodium"
39
Dry cough
ACE inhibitors
40
Pulmonary fibrosis
- Methotrexate - Nitrofurantoin - Carmustine - Bleomycin - Busulfan - Amiodarone "My Nose Cannot Breathe Bad Air"
41
Antimuscarinic
- Atropine - TCAs - H1 blockers - Anti-psychotics
42
Disulfiram-like reaction
- Metronidazole - Certain cephalosporins - Griseofulvin - Procarbaine - 1st generation sulfonylureas
43
Nephrotoxicity/ ototoxicity
- Aminoglycosides - Vancomycin - Loop diuretics - Cisplatin - Cisplatin toxicity may respond to amifostine
44
Coronary vasospasm
- Cocaine - Sumitriptan - Ergot alkaloids
45
Cutaneous flushing
- Vancomycin - Adenosine - Niacin - Ca2+ channel blockers - Enchinocandins "VANCE"
46
Dilated cardiomyopathy
- Anthracyclines (eg doxorubicin, daunorubicin) | - Prevent with dexrazoxane
47
Torsades de pointes
- AntiArrhythmics (class IA, III) - AntiBiotics (eg macrolides) - Anti"C"ychotics (eg haloperidol) - AntiDepressants (eg TCAs) - AntiEmetics (eg ondansetron) "ABCDE"