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USMLE 1 > Drug reactions > Flashcards

Drug reactions Flashcards

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USMLE® Step 1 flashcards
1
Q

coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids (ergonavine)

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2
Q

cutaneous flushing

A

vancomycin, adenosine, niacin, Calcium channel blockers

VANC

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3
Q

Dilated cardiomyopathy

A

doxorubicin, daunorubicin

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4
Q

torsades de pointes

A

Class III (sotalol) and class 1a (quinidine) antiarrhythmics, macrolides, antipsychotics, TCAs

(Some Queens Make Arrhythmias and Torsades)

Some Risky Meds Can Produce QT:
sotalol, risperidone, macrolides, chloroquine, protease inhibitors, quinidine, thiazides

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5
Q

hot flashes

A

tamoxifen, clomiphene

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6
Q

hyperglycemia

A

Tacrolimus, Protease inhibitors, Niacin, Hctz, Beta blockers, corticosteroids

Taking Pills Necessitates Having Blood Checked

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7
Q

hypothyroidism

A

Lithium, amiodarone, sulfonamides

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8
Q

Acute cholestatic hepatitis, jaundice

A

erythromycin

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9
Q

Diarrhea

A

Metformin, Erythromycin, Colchicine, Orlistat, Acarbose

Might Excite Colon On Accident

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10
Q

Focal to massive hepatic necrosis

A

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen

Liver HAVAc

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11
Q

Hepatitis

A

Isoniazid

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12
Q

Pancreatitis

A

Didanosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ)

Drugs Causing A Violent Abdominal Distress

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13
Q

Pseudomembranous colitis

A

Clindamycin, ampicillin, cephalosporins

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14
Q

Agranulocytosis

A

Dapsone, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthioruacil

Drugs CCCrush Myeloblasts and Promyelocytes

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15
Q

Aplastic anemia

A

Carbamazepine, methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil

Can’t Make New Blood Cells Properly

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16
Q

Direct-Coombs-positive hemolytic anemia

A

methyldopa, penicillin

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17
Q

Gray baby syndrome

A

Chloramphenicol

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18
Q

Hemolysis in G6PD deficiency

A

Isoniazid, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

Hemolysis IS D PAIN

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19
Q

Megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs

Having a blast with PMS

20
Q

Thrombocytopenia

A

Heparin, cimetidine

21
Q

Fat redistribution

A

Protease inhibitors, glucocorticoids

Fat PiG

22
Q

Gingival hyperplasia

A

Phenytoin, verapamil, cyclosporine, nifedipine

Very cold PHood numbs gums

23
Q

Hyperuricemia

A

Pyrazinamide, Thiazides, furosemide, Niacin, cyclosporine

Painful Tophi and Feet Need Care

24
Q

Myopathy

A

Fibrates, niacin, colchicine, hydroxychloroquine, interferon-alpha, penicillamine, statins, glucocorticoids

25
Q

Osteoporosis

A

Corticosteroids, heparin

26
Q

Photosensitivity

A

Sulfonamides, Amiodarone, tetracyclines, 5-FU

SAT for Photo

27
Q

Rash (stevens-johnson syndrome)

A

Anti-epileptic drugs (ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital), allopurinol, sulfa drugs, penicillin

Steven johnson has epileptic allergy to sulfa drugs and penicillin

28
Q

SLE-like syndrome

A

Sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin, etanercept

Having lupus is SHIPPE

29
Q

Teeth discoloration

A

tetracycline

30
Q

Tendonitis, tendon rupture, cartilage damage

A

Fluoroquinolones

31
Q

Cinchonism

A

(tinnitus, slight deafness, photophobia, mental dullness, depression, confusion, headache, nausea)

Quinidine, quinine

32
Q

Parkinson-like syndrome

A

Antipsychotics, reserpine, metoclopramide

33
Q

Seizures

A

Isoniazid (due to vit B6 deficiency), bupropion, imipenem/cilastatin, tramadol, enflurane, metoclopramide

with seizures, I BITE My tongue

34
Q

tardive dyskinesia

A

Antipsychotics, metoclopramide

35
Q

Diabetes insipidus

A

Lithium, demeclocycline

36
Q

Fanconi syndrome

A

(proximal tubule: glucose, aa, UA, PO4, HCO3 not being reabsorbed)

Expired tetracycline

37
Q

Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide

38
Q

Interstitial nephritis

A

Methicillin, NSAIDs, furosemide

39
Q

SIADH

A

Caramazepine, Cyclophosphamide, SSRIs

Can’t Concentrate Serum Sodium

40
Q

Dry cough

A

ACE inhibitors

41
Q

Pulmonary fibrosis

A

Bleomycin, Amiodarone, busulfan, methotrexate

Breathing Air Badly from Medications

42
Q

Antimuscarinic

A

Atropine, TCAs, H1 blockers, antipsychotics

43
Q

Disulfiram-like reaction

A

metronidazole, certain cephalosporins, griseofulvin, probarbazine, first generation sulfonylureas

44
Q

Nephrotoxicity and ototoxicity

A

Aminoglycosides, vancomycin, loop diruetics, cisplatin

45
Q

CYP inducers (nine)

A

Chronic alcohol use, modafinil, st john’s wort, phenytoin, phenobarbital, nevirapine, rifampin, griseofulvin, carbamazepine

Chronic alcoholic Mona STeals PHEN-PHEN and NEver Refuses GReasy CARBs

46
Q

Substrates for CYPs

A

Anti-epileptics, antidepressants, antipsychotics, anesthetics, theophyline, warfarin, statins, OCPs

A depressed, psychotic and epileptic anesthesiologist swallowed over the counter pills whenever tired.

47
Q

Inhibitors of CYPs

A

Acute alcohol abuse, gemfibrozil, ciprofloxacin, isoniazid, grapefruit juice, quinidine, amiodarone, ketoconazole, macrolides, sulfonamides, cimetidine, ritonavir

A CUTE GEntalman CIPped Iced Grapefruit juice QUIckly And Kept Munching on Soft Cinammon Rolls

USMLE 1 (7 decks)

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