Drug reactions Flashcards by Katie Dobberpuhl

coronary vasospasm

cocaine, sumatriptan, ergot alkaloids (ergonavine)

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cutaneous flushing

vancomycin, adenosine, niacin, Calcium channel blockers

VANC

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Dilated cardiomyopathy

doxorubicin, daunorubicin

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torsades de pointes

Class III (sotalol) and class 1a (quinidine) antiarrhythmics, macrolides, antipsychotics, TCAs

(Some Queens Make Arrhythmias and Torsades)

Some Risky Meds Can Produce QT:
sotalol, risperidone, macrolides, chloroquine, protease inhibitors, quinidine, thiazides

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hot flashes

tamoxifen, clomiphene

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hyperglycemia

Tacrolimus, Protease inhibitors, Niacin, Hctz, Beta blockers, corticosteroids

Taking Pills Necessitates Having Blood Checked

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hypothyroidism

Lithium, amiodarone, sulfonamides

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Acute cholestatic hepatitis, jaundice

erythromycin

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Diarrhea

Metformin, Erythromycin, Colchicine, Orlistat, Acarbose

Might Excite Colon On Accident

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Focal to massive hepatic necrosis

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen

Liver HAVAc

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Hepatitis

Isoniazid

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Pancreatitis

Didanosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ)

Drugs Causing A Violent Abdominal Distress

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Pseudomembranous colitis

Clindamycin, ampicillin, cephalosporins

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Agranulocytosis

Dapsone, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthioruacil

Drugs CCCrush Myeloblasts and Promyelocytes

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Aplastic anemia

Carbamazepine, methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil

Can’t Make New Blood Cells Properly

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Direct-Coombs-positive hemolytic anemia

methyldopa, penicillin

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Gray baby syndrome

Chloramphenicol

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Hemolysis in G6PD deficiency

Isoniazid, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

Hemolysis IS D PAIN

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Megaloblastic anemia

Phenytoin, Methotrexate, Sulfa drugs

Having a blast with PMS

Thrombocytopenia

Heparin, cimetidine

Fat redistribution

Protease inhibitors, glucocorticoids

Fat PiG

Gingival hyperplasia

Phenytoin, verapamil, cyclosporine, nifedipine

Very cold PHood numbs gums

Hyperuricemia

Pyrazinamide, Thiazides, furosemide, Niacin, cyclosporine

Painful Tophi and Feet Need Care

Myopathy

Fibrates, niacin, colchicine, hydroxychloroquine, interferon-alpha, penicillamine, statins, glucocorticoids

Osteoporosis

Corticosteroids, heparin

Photosensitivity

Sulfonamides, Amiodarone, tetracyclines, 5-FU SAT for Photo

Rash (stevens-johnson syndrome)

Anti-epileptic drugs (ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital), allopurinol, sulfa drugs, penicillin Steven johnson has epileptic allergy to sulfa drugs and penicillin

SLE-like syndrome

Sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin, etanercept Having lupus is SHIPPE

Teeth discoloration

tetracycline

Tendonitis, tendon rupture, cartilage damage

Fluoroquinolones

Cinchonism

(tinnitus, slight deafness, photophobia, mental dullness, depression, confusion, headache, nausea) Quinidine, quinine

Parkinson-like syndrome

Antipsychotics, reserpine, metoclopramide

Seizures

Isoniazid (due to vit B6 deficiency), bupropion, imipenem/cilastatin, tramadol, enflurane, metoclopramide with seizures, I BITE My tongue

tardive dyskinesia

Antipsychotics, metoclopramide

Diabetes insipidus

Lithium, demeclocycline

Fanconi syndrome

(proximal tubule: glucose, aa, UA, PO4, HCO3 not being reabsorbed) Expired tetracycline

Hemorrhagic cystitis

Cyclophosphamide, ifosfamide

Interstitial nephritis

Methicillin, NSAIDs, furosemide

SIADH

Caramazepine, Cyclophosphamide, SSRIs Can't Concentrate Serum Sodium

Dry cough

ACE inhibitors

Pulmonary fibrosis

Bleomycin, Amiodarone, busulfan, methotrexate Breathing Air Badly from Medications

Antimuscarinic

Atropine, TCAs, H1 blockers, antipsychotics

Disulfiram-like reaction

metronidazole, certain cephalosporins, griseofulvin, probarbazine, first generation sulfonylureas

Nephrotoxicity and ototoxicity

Aminoglycosides, vancomycin, loop diruetics, cisplatin

CYP inducers (nine)

Chronic alcohol use, modafinil, st john's wort, phenytoin, phenobarbital, nevirapine, rifampin, griseofulvin, carbamazepine Chronic alcoholic Mona STeals PHEN-PHEN and NEver Refuses GReasy CARBs

Substrates for CYPs

Anti-epileptics, antidepressants, antipsychotics, anesthetics, theophyline, warfarin, statins, OCPs A depressed, psychotic and epileptic anesthesiologist swallowed over the counter pills whenever tired.

Inhibitors of CYPs

Acute alcohol abuse, gemfibrozil, ciprofloxacin, isoniazid, grapefruit juice, quinidine, amiodarone, ketoconazole, macrolides, sulfonamides, cimetidine, ritonavir A CUTE GEntalman CIPped Iced Grapefruit juice QUIckly And Kept Munching on Soft Cinammon Rolls