Antidotes

Question 1

Acetaminophen

what is this antidote also used for?

Answer 1

N-acetylcysteine (replenishes glutatione)

Also used for prevent nephrotoxicity from CT contrast dye. Also a mucolytic agent for broncitis, CF or influenza

Question 2

AChE inhibitors and organophosphates

Answer 2

Atropine, followed by pralidoxime

Question 3

Amephatamines

Answer 3

are basic, give something to acidify urine - NH4Cl

Question 4

Antimuscarinic, anticholinergic agents

Answer 4

Phyostigmine salicylate, control hyperthermia

Question 5

Benzodiazepines

Answer 5

Flumazenil

Question 6

Beta blockers

Answer 6

Glucagon

Question 7

Carbon monoxide

Answer 7

100% oyxgen

Question 8

Copper, arsenic, gold

Answer 8

Penicillamine

Question 9

Cyanide

Answer 9

Nitrite + thiosulfate + hydroxocobalamin

Question 10

Digitalis

Answer 10

Anti-dig Fab fragments

Question 11

Heparin

Answer 11

Protamine sulfate

Question 12

Iron

Answer 12

Deferoxamine, deferasirox

Question 13

Lead

Answer 13

EDTA, dimercaprol, succimer, pencillamine

Question 14

Mercury, arsenic, gold

Answer 14

Dimercaprol, succimer

Question 15

Methanol, ethylene glycol (antifreeze)

Answer 15

Fomepizol> ethanol, dialysis

Question 16

Opioids

Answer 16

Naloxone

Question 17

Salicylates

Answer 17

NaHCO3 (alkalinize urine), dialysis

Question 18

TCAs

Answer 18

NaHCO3 (plasma alkalinization)

Question 19

tPA, streptokinase, urokinase

Answer 19

aminocaproic acid

Question 20

warfarin

Answer 20

Vitamin K, plasma (if active bleeding)