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Pharm > Drug reactions 0423FA > Flashcards

Drug reactions 0423FA Flashcards

1
Q

cardio: coronary vasospasm

A

cocaine.

sumatriptan.

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2
Q

cardio: cutaneous flushing

A

Vancomycin.
Adenosine.
Niacin.
CCB.

“VANC”

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3
Q

cardio: dilated cardiomyopathy

A

doxorubicin (adriamycin).

daunorubicin.

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4
Q

cardio: torsades de pointes

A 
class III (sotolol) and 
class IA (quinidine) antiarrhythmics.
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5
Q

hematologic: agranulocytosis

A 
Clozapine. 
Carbamazepine.
Colchicine.
Propylthiouracil.
Methimazole.
Dapsone.

“Agranulocytosis Can Certainly Cause Pretty Major Damage”

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6
Q

hematologic: aplastic anemia

A 
chloramphenicol.
benzene.
NSAIDs.
propylthiouracil.
methimazole.
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7
Q

hematologic: direct Coombs positive hemolytic anemia

A

methyldopa

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8
Q

hematologic: gray baby syndrome

A

chloramphenicol

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9
Q

hematologic: hemolysis in G6PD-deficient pts

A 
Isoniazid.
Sulfonamides.
Primaquine.
Aspirin.
Ibuprofen.
Nitrofurantoin.

“hemolysis IS PAIN”

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10
Q

hematologic: megaloblastic anemia

A

Phenytoin.
Methotrexate.
Sulfa drugs.

“having a blast with PMS”

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11
Q

hematologic: thrombotic complications

A

OCPs (estrogen, progestin)

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12
Q

resp: cough

A

ACE inhibitors

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13
Q

resp: pulmonary fibrosis

A

BLeomycin.
Amiodarone.
Busulfan.

“it’s hard to BLAB when you have pulmo fibrosis”

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14
Q

GI: acute cholestatic hepatitis

A

erythromycin

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15
Q

GI: focal to massive hepatic necrosis

A

Halothane.
Acetaminophen.
Valproic acid.
Amanita phalloides.

“liver HAVAc”

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16
Q

GI: hepatitis

A

isoniazid (INH)

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17
Q

GI: pseudomembranous colitis

A

clindamycin, ampicillin

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18
Q

endo/repro: adrenocortical insuff

A

glucocorticoid withdrawal - due to HPA suppression

19
Q

endo/repro: gynecomastia

A 
Spironolactone.
Digitalis.
Cimetidine.
Estrogens.
chronic Alcohol.
Ketoconazole.

“Some Drugs Create Extremely Awesome Knockers”

20
Q

endo/repro: hot flashes

A

tamoxifen, clomiphene

21
Q

endo/repro: hypothyroidism

A

lithium.
amiodarone.
sulfonamides.

22
Q

endo/repro: hyperglycemia

A

niacin.
tacrolimus.
protease inhibitors.

23
Q

MSS/CT: fat redistribution

A

glucocorticoids.

protease inhibitors.

24
Q

MSS/CT: gingival hyperplasia

A

phenytoin.

verapamil.

25
Q

MSS/CT: gout

A 
furosemide.
thiazides.
niacin.
cyclosporine.
pyrazinamide.
26
Q

MSS/CT: myopathies

A 
Fibrates.
Niacin.
Colchicine.
Hydroxychloroquine.
Interferon alpha.
Penicillamine.
Statins.
Glucocorticoids.

“Fish N CHIPS Gives you myopathies”

27
Q

MSS/CT: osteoporosis

A

corticosteroids.

heparin.

28
Q

MSS/CT: photosensitivity

A

Sulfonamides.
Amiodarone.
Tetracycline.

“SAT for a photo”

29
Q

MSS/CT: rash (SJS)

A 
Penicillin.
Ethosuxamide.
Carbamazepine.
Sulfa drugs.
Lamotrigine.
Allopurinol.
Phenytoin.
Phenobarbital.

“bad rash after PEC SLAPP”

30
Q

MSS/CT: SLE-like syndrome

A

Hydralazine.
INH.
Procainamide.
Phenytoin.

“it’s not HIPP to have lupus”

31
Q

MSS/CT: tendonitis, tendon rupture, cartilage damage (kids)

A

fluoroquinolones

32
Q

renal/GU: diabetes insipidus

A

lithium.

demeclocycline.

33
Q

renal/GU: Fanconi syndrome

A

expired tetracycline

34
Q

renal/GU: interstitial nephritis

A

methicillin.
NSAIDs.
furosemide.

35
Q

renal/GU: hemorrhagic cystitis

A

cyclophosphamide.
ifosfamide.

*prevent by coadmin with mesna

36
Q

renal/GU: SIADH

A

carbamazepine.

cyclophosphamide.

37
Q

neuro: cinchonism

A

quinidine.

quinine.

38
Q

neuro: parkinson like syndrome

A

antipsychotics.
reserpine.
metoclopramide.

39
Q

neuro: seizures

A

bupropion.
imipenem/cilastatin.
INH.

40
Q

neuro: tardive dyskinesia

A

antipsychotics

41
Q

multiorgan: antimuscarinic

A

atropine.
TCAs.
H1 blockers.
neuroleptics.

42
Q

multiorgan: disulfiram-like reaction

A

metronidazole.
certain cephalosporins.
procarbazine.
1G sulfonylureas.

43
Q

multiorgan: nephrotoxicity + ototoxicity

A

aminoglycosides.
vancomycin.
loop diuretics.
cisplatin.

Pharm (5 decks)

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