Drug Names (Topical Ocular Anesthetics)

Question 1

Cocaine

Answer 1

Excellent anesthetic but has too many toxicities

Question 2

Tetracaine 0.5%

Answer 2

Prototypical topical ocular anesthetic, though not used as often anymore
Causes the most stinging as well

Question 3

What is the trade name for Proparacaine?

Answer 3

Ophthaine

Question 4

Proparacaine (Ophthaine) 0.5%

Answer 4

Current drug of choice for topical LA

Causes the least stinging

Question 5

What is the trade name for Benoxinate?

Answer 5

Fluress

Available as a combination with flurosecein

Question 6

Benoxinate (Fluress) 0.4%

Answer 6

Combined with flurosecein; no documented cases of contamination so good at preventing it

Question 7

What is the trade name for Lidocaine?

Answer 7

Akten

Question 8

Lidocaine (Akten)

Answer 8

Anesthetic GEL that is an AMIDE derivative and not ester

Question 9

What are some trade names for Ibuprofen?

Answer 9

Advil
Motrin
Nuprin

Question 10

What is the trade name for Naproxen?

Answer 10

Naprosyn

Question 11

What is the trade name for Naproxen sodium?

Answer 11

Anaprox

Aleve

Question 12

What is the trade name for Fenoprofen?

Answer 12

Nalfon

Question 13

What is the trade name for Ketoprofen?

Answer 13

Orudis

Question 14

What is the trade name for Oxaprozin?

Answer 14

Daypro

Question 15

What is the trade name for Celecoxib?

Answer 15

Celebrex

Question 16

Name the topical ocular NSAIDs we use

Answer 16

o	Flurbiprofen (Ocufen) 0.03%
o	Ketorolac (Acuvail) 0.45% non preserved
o	Ketorolac (Acular LS) 0.4% 
o	Diclofenac (Voltaren) 0.1% Though this happens with the other compounds, this has the most history of ‘corneal melting’ along with ketorolac
o	Bromfenac (Bromday) 0.09% claims much lower irritation scores versus ketorolac
o	Nepafenac (Nevanac) 0.1% (Prodrug for amfenac; must be converted going through the cornea) – improved ocular penetration, new formulation 0.3%