Drug Metabolism Pt 5: Phase 2 Flashcards by Daniel Arreola | Brainscape

Q

Phase 2 reactions consist of:

A

Glucoronide Formation

Sulfate formation

Glutathione conjugation

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Q

What enzyme is involved in Glucoronide Formation?

A

UDP-Glucuronyl Transferase

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Q

What enzyme is involved in sulfate formation?

A

Sulfotransferase

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Q

What enzyme is involved in Glutathione Formation?

A

Glutathione Transferase

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Q

Draw the Glucoronide formation reaction.

A

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Q

Draw the sulfate formation reaction.

A

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Q

Draw the Glutathione conjugation mechanism.

A

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Q

Gluathione conjugate is further metabolized into

______ _____

A

mercapturic acids

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