Drug metabolism

Question 1

Metabolism of Adrenaline

Answer 1

By monoamine oxidase and other enzymes in the blood, liver and around nerve endings; excreted by the kidneys

Question 2

Metabolism of Aspirin

Answer 2

Converted to salicylate in the gut mucosa and liver; excreted mainly by the kidneys.

Question 3

Metabolism of Ceftriaxone

Answer 3

Excreted unchanged in urine (33%-67%) and in bile

Question 4

Metabolism of Fentanyl

Answer 4

Metabolised by the liver; excreted by the kidneys

Question 5

Metabolism of GTN

Answer 5

Metabolised by the liver

Question 6

Metabolism of Ipratropium Bromide

Answer 6

Excreted by the kidneys

Question 7

Metabolism of Ketamine

Answer 7

Metabolised by the liver and excreted by the kidneys

Question 8

Metabolism of Methoxyflurane

Answer 8

Metabolised by the liver and excreted mainly by the lungs

Question 9

Metabolism of Midazolam

Answer 9

Metabolised in the liver and excreted by the kidneys

Question 10

Metabolism of Misoprostol

Answer 10

Converted to active metabolite misoprostol acid in the blood. Metabolised in the tissues and excreted by the kidneys

Question 11

Metabolism of Morphine

Answer 11

Metabolised by the liver, excreted by the kidneys