Drug Interactions Flashcards
carbazepaine and contraceptives?
carbamezapine reduces contraceptive efficacy
levonogestrel and antiepiletics?
reduces seizure threshold
ssris reduce or increase inr?
increase
ssris and doacs?
Selective serotonin reuptake inhibitors (SSRIs) and direct oral anticoagulants (DOACs) can increase the risk of major bleeding, especially in the first month of taking both medications.
ssri and nsaids?
increase risk of bleeding
warfarin and nsaids
increase risk of bleeding
St John’s Wart and ssri
serotonin syndrome
St John’s Wart and warfarin
St John’s wort decreases the anticoagulant effect of Warfarin. Manufacturer advises avoid.
st johns wart and doac
St John’s wort is predicted to decrease the exposure to Apixaban.
enteral feeding and warfarin?
contains vit k - decreases inr
cranberry juice and warfarin?
Cranberry juice.
- Enhances anticoagulant effect. Avoid.
meropenem and sodium valproate
meropenem and sodium valproate reduces sodium valproate by 60-100%
iron tablets levo ?
4hours apart
ssri and triptans?
HEALTHPATHWAYS SAYS : Can be safely used in combination with selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), but still counsel about the symptoms of serotonin toxicity (e.g. agitation, muscle twitching or rigidity, sweating, diarrhoea) however this is exceedingly rare.
simvastatin important interactions. Do all these drug interactions apply for atorvastatin?
- clarithromycin and erythromycin - increases exposure to simvastatin
- colchicine - rhabdomyolsis
- deltaparin/fragmin and enoxiparin
- Diltiazem and verapmil
- all the conazoles (fungal)
yes. therefore if you have a man with gout flare up you HAVE TO TELL THEM TO STOP THEIR STATIN!
