drug induced pigmentation Flashcards
Type 1
Blue black discolorstion
most common
type 2
Similar colored pigmentation on normal skin of anterior shins.
type 1 and 2 minocycline pigmentation occur after 3 months to several years.
type 3
Least common type
generalized muddy brown pigemntation. acc in sun exposed areas.
tigecycline may prod similar hyperpig.
the ff may cause blue black pigmentstion of face extremities ear cartilage oral mucosa nails in 29% of pxs.
chloroquine
hydroxychloroquine
quinacrine
color of pigmentatation in quinacrine
yellow
percent of amiodarone w photosensitivity
30-57%
after tx w 3-6 months.
1-10% slate gray hyperpigmentation.
pAS: yellow brown granules
Clofazamine tx color
Pink discoloration.that grad becomes reddish blue or brown and is concentrated in pxs w hansens dx.
pas: Brown granular pigment.
drug induces lipofuscinosis.
zidovudine color
Blue or brown hyperpigmentation.
freq observed in nails.
lunula may be blue or whole nail playe become dark brown.
causes slate gray hyperpig in sun exposed areas after long periods of ingestion.
Chlorpromazine
thioridazine
imipramine
Clonipramine
heavy metals gold silver and bismuth produce what color of pigmentation
blue and slate gray
most common heavy metal induces pigmentstion seen by dermatologists
Silver
arsenical melanosis char by
Black, generalized pigmentation or pronouncoued truncal hyperpigmentation tht spares the face. w scattered depigmented macules that resemble raindrops.
ccb diltiazem distribution
severe photodistributed hyperpigmentation.
1 yrs after starting tx.
slate gray or gray blue macules and ptches on face ndck and forearms. perifollicular accentuation noted.
tx. stope drug
Bleaching cream if needed
suncreen
DRUGS thatcause LCV
PTU
hydralazine
drugs- serum sickness like reaction
cefaclor (1-2 %)
present w fever, uritcarial rash; arthralgia 1-3 weeks.
antibiotics - beta lactam and minocycline
