Drug group : Hypnotic

Question 1

Drug types

Answer 1

1. Benzodiazepines
2. Z-drugs
3. Choral deriviatives
4. Sedative antihistamines
5. Clomethiazole
6. Melatonin

Question 2

Drug names of benzodiazepines

Answer 2

1. Temazepam
2. Loprazolam
3. Flurazepam

Question 3

mechanism of action of benzodiazepines

Answer 3

1. enhance the activities of GABA
2. bind to specific benzodiazepine receptor sites and enhance GABA’s inhibitor effects on neuronal excitability
3. produces calming effects on the brain

Question 4

indications of benzodiazepines

Answer 4

1. short term relief from severe, diabling and distressing insomnia

Question 5

contra indic of benzodiazepines

Answer 5

1. Respiratory depression
2. Sleep apnea
3. renal impairment
4. history of addiction

Question 6

side effects of benzodiazepines

Answer 6

1. drowsiness + confusions
2. interacts with alcohol + opiods
3. highly addictive ( MAX 4 WEEK USE )
   tolerance can develop within days and withdrawl incl anxiety/sweating/psychosis + seizures

Question 7

Drug names of Z-drugs

Answer 7

1. Zopiclone

2. Zolpiderm

Question 8

mechanism of action of Z -drugs

Answer 8

1. short term relief from severe, disabling and distressing insomnia

Question 9

contraindic for Z-drugs

Answer 9

1. Respiratory depression
2. Sleep apnea
3. renal impairment
4. history of addiction

Question 10

side effects for Z-drugs

Answer 10

1. same as benzos

2. may intefere with immune system and increase the risk of malignancy