Drug delivery

Question 1

3 types of inhaler devices

Answer 1

pMDI, breathe acutated, dry powder inhalers

Question 2

what device can be used to help mediate acutation of pMDI?

Answer 2

Spacer

Question 3

What may patients experience when changing from a pMDI to a DPI?

Answer 3

Less sensation in the mouth and throat as previous, coughing may also occur

Question 4

MHRA alert wiht pMDI inhalers (2018)

Answer 4

risk of airway obstruction from aspiration of loose objects

Question 5

What type of breathing should be used when using a spacer?

Answer 5

Tidal breathing

Question 6

How often should a spacer be cleaned?

Answer 6

Once a month, with mild detergent

Question 7

How should a spacer be dried?

Answer 7

Air dry ( static created wiht towel drying)

Question 8

How often should a spacer be replaced?

Answer 8

every 6 to 12 months

Question 9

In asthma, how are nebulisers usually driven?

Answer 9

By oxygen

Question 10

Droplets with a mean mass of 1 - 5 microns are deposited where?

Answer 10

Airways, therefore appropriate for asthma

Question 11

Droplets with a mean mass of 1 - 2 microns are deposited where?

Answer 11

the alveoli

Question 12

What drug is not suitable for ultrasonic nebulisation?

Answer 12

Dornase alpha

Question 13

What are the best device options for children < 5?

Answer 13

pMDI + spacer/ facemask or if inappropriate nebuliser