DRUG CLASSIFICATION Flashcards

1
Q

Classes of anticancer drugs

A

Alkylating agents
Antimetabolites
Cytotoxic antibiotics
Plant-Derived Products
Enzymes
Hormonal agents
Miscellaneous agents
Monoclonal antibodies
Protein Kinase inhibitors
Immunomodulating agents
Cellular growth factors

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2
Q

Alkylating agents

A

Nitrogen mustards
Nitrosureas
Alkyl sulfonates
Platinum compounds
Ethylenimines and methylmelamines
Triazenes

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3
Q

Nitrogen mustards

A

Bendamustine
Etramustine
Chlorambucil
Cyclophosphamide
Mechlorethamine
Melphalan
Ifosfamide

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4
Q

Nitrosureas

A

Carmustine
Lomustine
Semustine
Streptozocin

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5
Q

Alkyl sulfonates

A

Busulfan

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6
Q

Ethylenimines and methylmelamines

A

Thiotepa
Altretamine (hexamethyl melamine)

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7
Q

Triazines

A

Dacarbazine
Procarbazine
Temozolamide

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8
Q

Platinum compounds

A

Cisplatin
Carboplatin
Oxaliplatin

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9
Q

Antimetabolites

A

Folate antagonists
Purine analogues
Pyrimidine analogues

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10
Q

Folate antagonists

A

Methotrexate
Premetrexed
Raltitrexed

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11
Q

Pyrimidine analogues

A

Capecitabine
Cytarabine
Decitabine
Gemcitabine
Azacitidine
Fluorouracil
Tegafur

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12
Q

Purine analogues

A

Cladribine
Clofarabine
Fludarabine
Azathioprine
Mercaptopurine
Nelarabine
Pentostatin
Thioguanine

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13
Q

Cytotoxic antibiotics

A

Anthracyclines
Bleomycin
Mitomycin C
Dactinomycin
Plicamycin
Trabectedin

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14
Q

Types of Plant-derived cancer drugs

A

Taxanes
Vinca alkaloids
Camptothecins
Epipodophyllotoxins

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15
Q

Taxanes

A

Paclitaxel
Docetaxel
Cabazitaxel

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16
Q

Vinca alkaloids

A

Vinblastine
Vincristine
Vindesine
Vinflurine
Vinorelbine

17
Q

Camptothecins

A

Irinotecan
Topotecan
Belotecan

18
Q

Epipodophyllotoxins

A

Etoposide
Teniposide

19
Q

Enzymes used in cancer

A

L-asparaginase

20
Q

Classification of Hormonal agents used in cancer

A

Agonists:
Glucocorticoids
Estrogens
Progestins
Somatostatin analogues

Antagonists:
Antiestrogens
Antiandrogens
5-alpha reductase inhibitors
GnRH analogues

21
Q

Glucocorticoids

A

Prednisolone
Dexamethasone

22
Q

Estrogens

A

Diethylstilbesterol
Ethinylestradiol

23
Q

Progestins

A

Megestrol
Northisterone
Medroxyprogesterone

24
Q

GnRH analogues

A

Goserelin
Naferelin
Buserelin
Leuprorelin
Triptorelin
Leuprolide

25
Q

Somatostatin analogues

A

Octreotide
Lanreotide
Pasireotide

26
Q

Antiandrogens

A

Flutamide
Bicalutamide
Cyproterone

27
Q

Antiestrogens

A

Tamoxifen
Toremifene
Fulvestrant

28
Q

Aromatase inhibitors

A

Steroidal
Exemestane
Formestane

Non-steroidal
Anastrazole
Letrozole

29
Q

5-alpha reductase inhibitors

A

Finasteride
Dutasteride

30
Q

GnRH antagonists

A

Abarelix
Degarelix
Cetrorelix
Ganirelix
Elagolix
Relugolix

31
Q

Protein kinase inhibitors

A

Imatinib
Erlotinib
Soratinib
Crizotinib
Axitinib
Dasatinib
Sunitinib
Gefitinib
Everolimus
Sorafenib
Tacrolimus

32
Q

Monoclonal antibodies

A

Panitumumab
Trastuzumab
Brentuximab
Ofatumumab
Rituximab
Bevacizumab
Catumaxomab
Nivolumab
Pembrolizumab
Atezolimumab
Ipilimumab

33
Q

Immunomodulating agents

A

Levamisole
Interferons
Interleukins

34
Q

Cellular growth factors

A

Filgrastim
Sargromastim

35
Q

Miscellanous

A

Hydroxyurea
Mitotane
Mitoxantrone
Bexarotene