Drug Cards- Sympathomimetics Flashcards
Epinephrine
Class
MOA
Class: Sympathomimetics
MOA: alpha 1 (Vasoconstriction)
beta 1 (Cardiac inotropy, chronotropy increase)
beta 2 (Bronchodilation)
Epinephrine
Indications (6)
-cardiac arrest
-anaphylaxisis
-bradycardia
-severe refractory wheezing
-hypoperfusion
-croup/bronchiolitis
Epinephrine
Contraindications (A3 R5)
-hypersensitivity
-coronary artery disease
-cardio myopathy
-uncontrolled hypertension
-hypothermia
-pulmonary edema
-myocardial ischemia
-hypovlomeic shock
Epinephrine
Adverse Reactions (11)
-headache
-restlessness/nervousness
-tremor
-dysrhythmias
-chest pain
-increased myocardial o2 demand
-hypertension
-palpitations
-nausea/vomiting
Epinephrine
Drug Interactions (4)
-potentiates other sympathomimetics
-deactivated by alkaline solutions
-MAOI’s and anti-depressants may potentiate its effects
-bet blockers may blunt its affects
Epinephrine
IM Dose
Adult: 0.3-0.5mg
Peds: 0.01mg/kg
Epinephrine
Onset
Peak
Duration
Onset: <2min IV
3-10 min IM
Peak: <5min IV
20min IM
Duration: 5-10min IV
20-30min IM
Albuteral
Class
MOA
Class: Sympathomimetic
MOA: selective beta-2 agonist, causes bronchial smooth muscle relaxation. also inhibits mediator (inflammation causing) release.
Albuteral
Indications (3)
-bronchospasm with asthma or COPD
-inhaled airways irritants
-hyperkalemia
Increases activity of the sodium potassium pump
Albuteral
Contraindications (3)
-hypersensitivity
-dysrhythmias
-synergistic with other sympathomimetics
Albuteral
Adverse Reactions (10)
-nervousness
-tremors
-dizziness
-dysrhythmisa
-chest discomfort
-palpatations
-nausea/vomiting
-drymouth
Albuteral
Drug Interactions (4)
-tricyclic anti-depressants
-MAOI’s
-other sympathomimetics
-diuretics
Albuteral
Dose
Adult: RespDi- 2.5-5mg
RespDi- 5mg
Hyperkalemia- 5mg
Peds: Mild asthma, anaphylaxis, hyperkalemia- 2.5-5mg
RespDi- 5mg
Albuteral
Onset
Peak
Duration
Onset: 5-15min
Peak: 30min-2hrs
Duration: 3-6hrs
Epinephrine
IV Cardiac Arrest Dose
Adult: 1mg
Ped: 0.01mg/kg
