Drug Allergy Flashcards
1
Q
What can drug reactions be
A
Immediate
Delayed
Idiosyncratic reactions
2
Q
What ar the immediate reactions that can occur in drug reactions
A
Urticaria Angioedema Low BP Wheeze Hoarse voice Confusion Vomiting and diarrhoea
3
Q
What are the delayed reactions in drug allergy
A
Variety of rashes Itching Unexplained fever GI upset Arthralgia Myalgia
4
Q
What are idiosyncratic durg reactions
A
Steven Johnsons syndrome
Toxic epidermal necrolysis
Haemolysis- breakdown of RBC
5
Q
What is the most common drug allergy
A
Penicillin
6
Q
How do we manage severe drug reactions
A
Advise patient to wear medical alert bracelet
Train patient with adrenalin auto injector
7
Q
How do we investigate drug reactions
A
Measure tryptase at least 2 and 24 hours post reaction
Look at FBC: for haemolysis, eosinophillia and platelets
Look at renal and live function
