Dr.raeed Flashcards

1
Q

name the drugs that causes Gerd

A

nitroglycerine
calcium channel blockers
Diazepam
theophylline
TCA
Anticholinergics
a antagonists

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2
Q

name the drugs which is harmful to the esophegeal epithelium

A

tetracycline
NSAIDs
phosphate

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3
Q

name the drugs that elevate the motality of the inferior esophegeal sphincter

A

Metoclopramide
Domperidone

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4
Q

what are the indications of the surgical repairing to GERD

A

esophegeal stenosis
sever inflammation
deep ulcer

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5
Q

what are the GERD red flags

A

Odynophagia
unintentional weight loss (5kg in 6months)
GIT bleeding

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6
Q

what are the pulmonary symptoms if GERD

A

hoarsness
dry cough
pulmonary stenosis& inflammation
asthma
wheeze& bronchiospasm

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7
Q

what are the pulmonary symptoms if GERD

A

hoarsness
dry cough
pulmonary stenosis& inflammation
asthma
wheeze& bronchiospasm

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8
Q

what are the histological features of barrett’s esophagus

A

intestinal metaplasia & Goblet cells

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9
Q

symptoms of infectious esophegatitis

A

Dysphagia
Odynophagia
Bleeding
Fever

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10
Q

what are the causes of Granulomatus Esophagitis

A

tuberculosis & chron’s disease
syphlis
sarcoidosis

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11
Q

what are the complication of Esophagitis due to chemical injury

A

Bleeding
strictures
perforation
SCC

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12
Q

symptoms of Eosinophilic Esophagitis

A

vomitting & epigastric pain
Dysphagia
heart burn may exist

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13
Q

liver tests in chronic liver inflammation

A

elevated Alt & Ast
bilirubin normal or slightly elevated
Alp normal or slightly elevated
Immunoglobulins are normal or slightly elevated

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14
Q

the first sign in echo incase of chronic inflammation of the liver

A

nodular enlargement in the hilum of the liver

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15
Q

Alt & Ast in chronic liver inflammation

A

Alt >Ast. chronic inflammation (early or middle stages)
Ast> Alt. late stages of the disease and the patient is about to have a cirrhosis

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16
Q

how to diagnose chronic HBV

A

intermittent or continous elevation of Alt& Ast
+HBsAg
liver biopsy shows fibrosis & necrosis
+HBV-DNA

17
Q

HBV drugs

A

IFN-2a & IFN-2b
lamivudune, Telbivudine and Entecavir are Necleosidic
Adefovir Dipivoxil (ADV), Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide(TAF) are non necleotidic

18
Q

what are the complications of IFN treatment in HBV

A

depletion in WBCS count
disturbances in thyroid functions
depression
hair loss
thrombocytopenia
eractile dysfunction
MI & arrythmias
induction of dormant autoimmune diseases