Dr.Patel-OrganTrans/Pulm Flashcards
What are the three most important DENTAL considerations for patients who have undergone an organ transplant?
1.Bleeding 2.infection 3.build up of drugs/toxic metabolites (liver/kidney)
What are the two most common immunosuppressive drugs?
prednisone and cyclosporine
What are these signs indicating? Infections (viral, bacterial, fungal), Delayed healing, Excessive bleeding, HTN
OVER-immunosuppression
What are 7 oral signs of immunosuppression?
1.Mucositis 2.HSV 3.Apthous ulcers 4.CMV 5.Candidiasis 6.tumor development 7.Bone loss
How long does it take a HSCT patient to become immunocompetent?
1 year
What are the 4 most common VIRAL infections in immunocompromised patients?
1.Hep (B/C) 2.HIV 3.HSV 4.CMV
What are the three most common BACTERIAL infections in immunocompromised patients?
1.Staph 2. UTI 3.TB
Which drug causes bone marrow suppression (leukopenia, thrombocytopenia, anemia), increased risk for infection?
AZ-ath-io-PRiNE
Which drug affects liver and kidney (HTN, bleeding abnormalities, anemia), GINGIVAL HYPERPLASIA, skin/cervical cancer
cyclosporine
Which drug? Anti-thymocyte, Anti-lymphocyte ______: fever, leukopenia, hemolysis, thrombocytopenia, tumor development, increased risk for infection
globulin
Which drug is this describing??? HTN, DM II, osteoporosis, impaired healing, mental depression, psychoses, adrenal suppression increased risk for infection
Prednisone
If a patient is undergoing Graft vs Host disease, when is a Acute reaction likely to take place?
within 2 months
***How long do we DELAY dental care post-transplant?
6 months
PRE-transplant MED consult: establish ______ of organ dysfunction, need for prophy abx, and any labs needed.
degree
What are the two antibiotics for organ transplant patients?
amoxicillin and metroNidAZole
What prophy abx are given if the patient is allergic to penicillin?
Vancomycin
What are the 4 common dental drugs to avoid for patients waiting to undergo a kidney transplant?
Acetaminophen, Penicillin, Cephalexin, and Tetracycline
What is the protocol if we are concerned about a patient undergoing adrenal crisis?
give corticosteroids before the procedure
Are there treatment planning modifications needed for patients with asthma?
Nope
Asthma Emergency? Short-acting _________ agent (Ventolin or Proventil) is recommended
beta 2-adrenergic
What are the 2 types of COPD?
Chronic Bronchitis and Emphysema
A patient is considered to be COPD unstable when their O2 saturation level is less than ___%
91%
What is a oxygen % you would like a COPD patient above, and therefor would supplement with O2 if not to that level?
95%
Is nitrous oxide contraindicated in patients with COPD? What can be used for sedation?
it is a RELATIVE contraindication…low does diazepam is ok
Are there major treatment planning modifications with COPD?
Nope
What is the rare syndrome associated with Theophylline??
Stevens-Johnson syndrome
