Dr.Patel-OrganTrans/Pulm Flashcards
What are the three most important DENTAL considerations for patients who have undergone an organ transplant?
1.Bleeding 2.infection 3.build up of drugs/toxic metabolites (liver/kidney)
What are the two most common immunosuppressive drugs?
prednisone and cyclosporine
What are these signs indicating? Infections (viral, bacterial, fungal), Delayed healing, Excessive bleeding, HTN
OVER-immunosuppression
What are 7 oral signs of immunosuppression?
1.Mucositis 2.HSV 3.Apthous ulcers 4.CMV 5.Candidiasis 6.tumor development 7.Bone loss
How long does it take a HSCT patient to become immunocompetent?
1 year
What are the 4 most common VIRAL infections in immunocompromised patients?
1.Hep (B/C) 2.HIV 3.HSV 4.CMV
What are the three most common BACTERIAL infections in immunocompromised patients?
1.Staph 2. UTI 3.TB
Which drug causes bone marrow suppression (leukopenia, thrombocytopenia, anemia), increased risk for infection?
AZ-ath-io-PRiNE
Which drug affects liver and kidney (HTN, bleeding abnormalities, anemia), GINGIVAL HYPERPLASIA, skin/cervical cancer
cyclosporine
Which drug? Anti-thymocyte, Anti-lymphocyte ______: fever, leukopenia, hemolysis, thrombocytopenia, tumor development, increased risk for infection
globulin
Which drug is this describing??? HTN, DM II, osteoporosis, impaired healing, mental depression, psychoses, adrenal suppression increased risk for infection
Prednisone
If a patient is undergoing Graft vs Host disease, when is a Acute reaction likely to take place?
within 2 months
***How long do we DELAY dental care post-transplant?
6 months
PRE-transplant MED consult: establish ______ of organ dysfunction, need for prophy abx, and any labs needed.
degree
What are the two antibiotics for organ transplant patients?
amoxicillin and metroNidAZole