Drosophila Sensory organs development Flashcards
What does Drosophila sense with: antenna sensory bristles mouthparts oviposition tarsae?
olfaction, hearing touch gustation gustation, touch gustation, touch
What do adult tissues in the larva develop from?
imaginal discs
What are the 5 stages of sensory organ development?
- defining a large region where sense organs will develop
- defining smaller reions of neural competence
- singling out a sensory precursor cell
- lineage control and asymmetric divisions
- establishing correct neuronal connections
Which genes define large regions where sense organs will develop and which then define smaller regions of neural competence?
pre-patterning genes
proneural
Name 3 pre-patterning genes.
iroquois
pannier
u-shaped
Name 3 proneural genes.
achaete, scute, atonal
How is expression of achaete and scute determined?
first patchy
then refined by regulatory elements responding to iroquois
How is the single sensory precursor cell chosen?
by mutal inhibition among proneural cells which leads to emergence of a single sensory organ precursor per group
Which pathway is responsible for mutal inhibition?
Expression of which proneural gene promotes it?
Notch-Delta
Scute promotes Delta expression (more Delta = win)
What does a term “fixed lineage” mean?
pattern and number of divisions is constant for a given type of sensory organ
In Drosophila sensory organ development, which cells are generated from a single precursor cell?
bristle cell
socket cell
glial (sheat) cell
1 or more neurons
Where do the sensory neurons from the bristle extend to?
Which gene controls the projections?
ventral nerve chord
iroquois
What happens with proneural cell that were not chosen for precursors?
return to epidermal fate
