Dr. Sarko's Neuro Lab VI

Question 1

Septal Nuclei afferents

Answer 1

Fornix, from hippocampus

Stria terminalis, ventral amygdalofugal pathway

Question 2

Septal nuclei efferents

Answer 2

Hippocampus (cholinergic, via fornix)

Hypothalamus parasympathetic centers and midbrain (via medial forebrain bundle)

Habenula of thalamus (via stria terminalis, which then sends signal about pleasure to the ventral tegmental area via the fasciculus retroflexus)

Question 3

Septal Nuclei function/lesion

Answer 3

Functions in pleasure

Without it, sham rage occurs

Question 4

Amygdala Afferents

Answer 4

Hypothalamus (via ST & VAF)
Septal Nuclei (via ST)
Thalamus (via VAF)
Anterior cingulate (via VAF)

Question 5

Amygdala Efferents

Answer 5

Amygdala Efferents are reciprocal to it’s afferents

Some project directly to the hippocampus and cortical areas

Question 6

Amygdala function and lesion

Answer 6

Involved in fear and autonomic functions. Without it, fearlessness or absence of emotional responses would occur

Question 7

Nucleus Accumbens Afferents

Answer 7

Ventral Tegmental Area (via MFB)

Question 8

Nucleus Accumbens Efferents

Answer 8

Pre-frontal cortex

Question 9

Nucleus accumbens Function and Lesion

Answer 9

Functions in reward, motivation and satisfaction.

Amotivation and anhedonia may occur without it